Brain Abscess

Bai, James; Bangiyev, Lev

doi:10.1007/978-3-319-65106-4_120

Cited by 2 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The incidence of cerebral abscess is around 8% of the total intracranial mass incidence in developing countries, while the incidence in developed countries is only 1%-2%. Most cases in developing countries occur in the group of 0-20 years old [8], [9]. In this study, we found that the mortality rate of cerebral abscess patients with a history of CHD is 38.3%.…”

Section: Discussionmentioning

confidence: 49%

Factors Associated with Mortality in Children with Congenital Heart Disease and Cerebral Abscess

Rahayuningsih

Kuswiyanto²,

Apandi³

et al. 2023

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND: In children, a cerebral abscess is a rare yet life-threatening condition. Children account for about 25% of all cerebral abscess cases in the general population. One of the most common predisposing factors for developing a cerebral abscess with increased mortality risk is congenital heart disease (CHD). AIM: This study aims to determine the prevalence of death and factors associated with death in children with CHD and cerebral abscesses. METHODS: This study is a cross-sectional design which collects retrospective data. Secondary data of CHD patients with cerebral abscesses were retrieved from patients’ medical records. RESULTS: From January 1, 2012, to December 31, 2021, a total of 107 children with a history of CHD were diagnosed with cerebral abscesses during this study. Thus, mortality rates in cases with cerebral abscess were 38.3% in children with a history of CHD. Patients with a focal infection in the ear, nose, and throat (ENT) area have a 3.6 times higher risk of dying than those with a focal infection elsewhere (odds ratio [OR] = 3.6 [95% confidence interval [CI], 1.57–8.32, p = 0.004). Patients who did not have neurosurgery had a 2.5- fold increased risk of death than those who did (OR = 2.5, 95% CI, 1.11–5.96, p < 0.05). Nutritional status, anemia status, and culture results, which were anticipated to be linked with death in CHD children with cerebral abscess, were not statistically significant. CONCLUSION: We conclude that this study provides an overview of the prevalence of mortality and variables related to death in incidents of cerebral abscess in children with CHD in Indonesia.

show abstract

Section: Discussionmentioning

confidence: 49%

Factors Associated with Mortality in Children with Congenital Heart Disease and Cerebral Abscess

Rahayuningsih

Kuswiyanto²,

Apandi³

et al. 2023

Open Access Maced J Med Sci

View full text Add to dashboard Cite

show abstract

“…It usually results from infectious processes such as mastoiditis, orbital cellulitis, intraoral infection, or, rarely, traumatic or surgical events. Its association with CHD is usually seen in young patients [ 10 ]. In CCHD patients, particularly those with TOF, brain abscesses occur due to hematogenous spread of infection facilitated by right-to-left shunting.…”

Section: Discussionmentioning

confidence: 99%

“…Chronic hypoxia and metabolic acidosis due to secondary polycythemia cause hypo-perfusion of the brain, allowing the pathogens to seed under such hypo-perfused regions, further predisposing patients to infections [ 11 ]. Common pathogens causing brain abscesses in adults include streptococcus species, staphylococcus species, gram-negative bacteria, and anaerobic bacteria [ 10 ]. Brain abscesses can lead to elevated intracranial pressure and carries significant morbidity and mortality.…”

Section: Discussionmentioning

confidence: 99%

“…The antibiotic regimen should be selected carefully based on the microorganisms isolated from blood or CSF. Antibiotics, like first-generation cephalosporins, aminoglycosides, and tetracyclines, are ineffective in treating brain abscesses as they cannot cross the blood-brain barrier [ 10 ]. When treating a surgically repaired abscess, antibiotics are recommended for four to six weeks; and in case of large multiple abscesses or an abscess treated medically, they are recommended for six to eight weeks [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Rare Confluence: Brain Abscess in an Adult With Tetralogy of Fallot

Gupta,

Singh,

Vashisht

et al. 2024

Cureus

View full text Add to dashboard Cite

Tetralogy of Fallot (TOF) is a common congenital heart disease (CHD) characterized by four distinct cardiac abnormalities. Brain abscess, though rare, is a life-threatening complication in patients with cyanotic congenital heart disease (CCHD), including TOF. This case report describes a 24-year-old female with unrepaired TOF who presented with symptoms of a brain abscess, including altered sensorium, fever, projectile vomiting, and headache. Diagnostic imaging with non-contrast-enhanced computed tomography (NCCT) revealed a well-defined hypodense lesion with a midline shift, prompting urgent drainage of the abscess. Subsequent cultures of the pus material identified Streptococcus intermedius as the causative agent, and the patient was maintained on antibiotics. This case highlights the importance of early diagnosis and surgical repair of TOF to prevent severe complications such as brain abscess, thereby reducing morbidity and mortality.

show abstract

Brain Abscess

Cited by 2 publications

References 2 publications

Factors Associated with Mortality in Children with Congenital Heart Disease and Cerebral Abscess

Factors Associated with Mortality in Children with Congenital Heart Disease and Cerebral Abscess

A Rare Confluence: Brain Abscess in an Adult With Tetralogy of Fallot

Contact Info

Product

Resources

About