Brain Activation in Primary Motor and Somatosensory Cortices during Motor Imagery Correlates with Motor Imagery Ability in Stroke Patients

Confalonieri, Linda; Pagnoni, Giuseppe; Barsalou, Lawrence W.; Rajendra, Justin; Eickhoff, Simon B.; Butler, Andrew

doi:10.5402/2012/613595

Cited by 46 publications

(38 citation statements)

References 70 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is not known whether being able to perform MI tasks is necessary to gain benefit from it in clinical practice (8,9). Moreover, Confalonieri et al report that motor imagery stimulates sensorimotor and pre-motor areas even in poor imagers with stroke (25). In our study we found no correlation between motor imagery ability (as reflected by initial MIQ-RS scores) and our outcome measure of gait velocity improvement after motor imagery training.…”

Section: Effect Of Motor Imagery Training On Motor Imagery Abilitycontrasting

confidence: 51%

Influence of motor imagery training on gait rehabilitation in sub-acute stroke: A randomized controlled trial

Oostra

Oomen²,

Vanderstraeten³

et al. 2015

J Rehabil Med

View full text Add to dashboard Cite

Objective: To evaluate the effect of mental practice on motor imagery ability and assess the influence of motor imagery on gait rehabilitation in sub-acute stroke. Design: Randomized controlled trial. Subjects: A total of 44 patients with gait dysfunction after first-ever stroke were randomly allocated to a motor imagery training group and a muscle relaxation group. Methods: The motor imagery group received 6 weeks of daily mental practice. The relaxation group received a muscle relaxation programme of equal duration. Motor imagery ability and lower limb function were assessed at baseline and after 6 weeks of treatment. Motor imagery ability was tested using a questionnaire and mental chronometry test. Gait outcome was evaluated using a 10-m walk test (near transfer) and the Fugl-Meyer assessment (far transfer). Results: Significant between-group differences were found, with the vividness of kinesthetic imagery and the walking test results improving more in the motor imagery group than in the muscle relaxation group. There was no group interaction effect for the far transfer outcome score. Conclusion: Motor imagery training may have a beneficial task-specific effect on gait function in sub-acute stroke; however, longer term confirmation is required.

show abstract

Section: Effect Of Motor Imagery Training On Motor Imagery Abilitycontrasting

confidence: 51%

Influence of motor imagery training on gait rehabilitation in sub-acute stroke: A randomized controlled trial

Oostra

Oomen²,

Vanderstraeten³

et al. 2015

J Rehabil Med

View full text Add to dashboard Cite

show abstract

“…Previous studies (Page et al, 2001 ; Butler and Page, 2006 ; Confalonieri et al, 2012 ) have shown that the combination of MP and PT is helpful in improving functional and motor skills more than MP only. MP by itself is considered an effective technique to enhance motor performance by tracing the overlap between motor imagery and motor execution neural circuits (Jeannerod, 2006 ).…”

Section: Discussionmentioning

confidence: 96%

Functional organization and restoration of the brain motor-execution network after stroke and rehabilitation

Bajaj

Butler

Drake

et al. 2015

Front. Hum. Neurosci.

Self Cite

View full text Add to dashboard Cite

Multiple cortical areas of the human brain motor system interact coherently in the low frequency range (<0.1 Hz), even in the absence of explicit tasks. Following stroke, cortical interactions are functionally disturbed. How these interactions are affected and how the functional organization is regained from rehabilitative treatments as people begin to recover motor behaviors has not been systematically studied. We recorded the intrinsic functional magnetic resonance imaging (fMRI) signals from 30 participants: 17 young healthy controls and 13 aged stroke survivors. Stroke participants underwent mental practice (MP) or both mental practice and physical therapy (MP+PT) within 14–51 days following stroke. We investigated the network activity of five core areas in the motor-execution network, consisting of the left primary motor area (LM1), the right primary motor area (RM1), the left pre-motor cortex (LPMC), the right pre-motor cortex (RPMC) and the supplementary motor area (SMA). We discovered that (i) the network activity dominated in the frequency range 0.06–0.08 Hz for all the regions, and for both able-bodied and stroke participants (ii) the causal information flow between the regions: LM1 and SMA, RPMC and SMA, RPMC and LM1, SMA and RM1, SMA and LPMC, was reduced significantly for stroke survivors (iii) the flow did not increase significantly after MP alone and (iv) the flow among the regions during MP+PT increased significantly. We also found that sensation and motor scores were significantly higher and correlated with directed functional connectivity measures when the stroke-survivors underwent MP+PT but not MP alone. The findings provide evidence that a combination of mental practice and physical therapy can be an effective means of treatment for stroke survivors to recover or regain the strength of motor behaviors, and that the spectra of causal information flow can be used as a reliable biomarker for evaluating rehabilitation in stroke survivors.

show abstract

“…The first two images of every EPI-recording session were discarded to account for the approach to steady state in the MR signal. Prior to image analysis, each participant's raw data of fMRI scan were motion-corrected and normalized, similar to the previous study [37]. The amount of absolute motion did not exceed 1 mm for any participant.…”

Section: Methodsmentioning

confidence: 99%

Early and Late Shift of Brain Laterality in STG, HG, and Cerebellum with Normal Aging during a Short-Term Memory Task

et al. 2013

View full text Add to dashboard Cite

Evidence suggests that cognitive performance deteriorates in noisy backgrounds and the problems are more pronounced in older people due to brain deficits and changes. The present study used functional MRI (fMRI) to investigate the neural correlates of this phenomenon during short-term memory using a forward repeat task performed in quiet (STMQ) and in noise: 5-dB SNR (STMN) on four groups of participants of different ages. The performance of short-term memory tasks was measured behaviourally. No significant difference was found across age groups in STMQ. However, older adults (50–65 year olds) performed relatively poorly on the STMN. fMRI results on the laterality index indicate changes in hemispheric laterality in the superior temporal gyrus (STG), Heschl's gyrus (HG), and cerebellum, and a leftward asymmetry in younger participants which changes to a more rightward asymmetry in older participants. The results also indicate that the onset of the laterality shift varies from one brain region to another. STG and HG show a late shift while the cerebellum shows an earlier shift. The results also reveal that noise influences this shifting. Finally, the results support the hypothesis that functional networks that underlie STG, HG, and cerebellum undergo reorganization to compensate for the neural deficit/cognitive decline.

show abstract

Brain Activation in Primary Motor and Somatosensory Cortices during Motor Imagery Correlates with Motor Imagery Ability in Stroke Patients

Cited by 46 publications

References 70 publications

Influence of motor imagery training on gait rehabilitation in sub-acute stroke: A randomized controlled trial

Influence of motor imagery training on gait rehabilitation in sub-acute stroke: A randomized controlled trial

Functional organization and restoration of the brain motor-execution network after stroke and rehabilitation

Early and Late Shift of Brain Laterality in STG, HG, and Cerebellum with Normal Aging during a Short-Term Memory Task

Contact Info

Product

Resources

About