Brain chemistry reflects dual states of pain and anxiety in chronic low back pain

Apkarian, A. Vania; Frederickson, Bruce; Grachev, Igor D.

doi:10.1016/s1053-8119(01)90017-5

Cited by 3 publications

(2 citation statements)

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“…Previously, understanding pain involved using the end-organ dysfunction model, in which structural abnormalities at the pain-causing site were deemed to be the root cause [ 127 ]. In terms of this model, pain is relieved through correcting or removing the structural abnormality that caused pain owing to tissue damage or inflammation.…”

Section: Changes In How Pain Is Viewedmentioning

confidence: 99%

“…With the recent introduction of the altered nervous system processing model, which views pain as a pain signal processing problem in the altered nervous system, various pain phenomena can be better understood. Problems encoding or processing sensory information correspond to this model, and physiological changes, genetic predisposition, and psychiatric variables are used for interpretation in this model [ 127 ]. Functional MRI for patients with back pain sometimes shows reduced brain volume or areas of activity that are not observed in healthy individuals, and such findings have changed the approach to pain that viewed it as being a structural spinal issue [ 128 , 129 , 130 ].…”

Section: Changes In How Pain Is Viewedmentioning

confidence: 99%

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Spinal Injections: A Narrative Review from a Surgeon’s Perspective

Shin,

Choo,

Chang

2023

Healthcare

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Spinal pain is one of most frequent complaints of the general population, which can cause decreased activities of daily living and absence from work. Among numerous therapeutic methods, spinal injection is one of the most effective treatments for spinal pain and is currently widely applied in the clinical field. In this review, spinal injection is discussed from a surgeon’s perspective. Recently, although the number of spinal surgeries has been increasing, questions are arising as to whether they are necessary. The failure rate after spinal surgery is high, and its long-term outcome was reported to be similar to spinal injection. Thus, spinal surgeries should be performed conservatively. Spinal injection is largely divided into diagnostic and therapeutic blocks. Using diagnostic blocks, such as the diagnostic selective nerve root block, disc stimulation test, and diagnostic medial branch block (MBB), the precise location causing the pain can be confirmed. For therapeutic blocks, transforaminal nerve root injection, therapeutic MBB, and percutaneous epidural neuroplasty are used. When unbearable spinal pain persists despite therapeutic spinal injections, spinal surgeries can be considered. Spinal injection is usefully used to identify the precise location prior to a patient undergoing injection treatment or surgery and can reduce pain and improve quality of life, and help to avoid spinal surgery. Pain physicians should treat patients with spinal pain by properly utilizing spinal injection.

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Section: Changes In How Pain Is Viewedmentioning

confidence: 99%

Section: Changes In How Pain Is Viewedmentioning

confidence: 99%

Spinal Injections: A Narrative Review from a Surgeon’s Perspective

Shin,

Choo,

Chang

2023

Healthcare

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Automatic localization of AC and PC landmarks in T2-weighted MR volumetric neuroimages

Zhang

Wang

et al. 2010

The 2010 IEEE International Conference on Information and Automation

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Développement de la dominance cérébrale : revue des données disponibles et proposition d'une hypothèse originale

Habib¹

2009

Développements

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Brain chemistry reflects dual states of pain and anxiety in chronic low back pain

Cited by 3 publications

References 0 publications

Spinal Injections: A Narrative Review from a Surgeon’s Perspective

Spinal Injections: A Narrative Review from a Surgeon’s Perspective

Automatic localization of AC and PC landmarks in T2-weighted MR volumetric neuroimages

Développement de la dominance cérébrale : revue des données disponibles et proposition d'une hypothèse originale

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