Brain death: time for an international consensus

Smith, Martin

doi:10.1093/bja/aer355

Cited by 46 publications

(36 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is no sufficient evidence to determine the minimally acceptable observation period between clinical exams; role of newer ancillary tests and safety of apnea test techniques. [3439] Future research should be directed towards these issues. Although guidelines are available in many countries for the diagnosis of brain-death, the variations and inconsistencies necessitate an international consensus and uniform guidelines.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Brainstem death: A comprehensive review in Indian perspective

Dhanwate¹

2014

Indian Journal of Critical Care Medicine

View full text Add to dashboard Cite

With the advent of cardiopulmonary resuscitation techniques, the cardiopulmonary definition of death lost its significance in favor of brain death. Brain death is a permanent cessation of all functions of the brain in which though individual organs may function but lack of integrating function of the brain, lack of respiratory drive, consciousness, and cognition confirms to the definition that death is an irreversible cessation of functioning of the organism as a whole. In spite of medical and legal acceptance globally, the concept of brain death and brain-stem death is still unclear to many. Brain death is not promptly declared due to lack of awareness and doubts about the legal procedure of certification. Many brain dead patients are kept on life supporting systems needlessly. In this comprehensive review, an attempt has been made to highlight the history and concept of brain death and brain-stem death; the anatomical and physiological basis of brain-stem death, and criteria to diagnose brain-stem death in India.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Some authors view this new term as philosophically neutral and physiologically clearer, while others find it unhelpful. [3334] The council rejects 1968 Harvard committee's social construct approach and also the higher brain approach. The council proposed a new-unifying concept of death.…”

Section: Historical Glimpsementioning

confidence: 99%

Brainstem death: A comprehensive review in Indian perspective

Dhanwate¹

2014

Indian Journal of Critical Care Medicine

View full text Add to dashboard Cite

show abstract

“…In the UK, the diagnosis of brain death in adult patients remains based on comprehensive clinical examination, the exclusion of potential confounders (including a sufficient time of observation), and confirmation of complete loss of brain stem function. 6 The final and most important observation in this case is that ultrasonographic and EEG evidence of cerebral circulatory arrest and cortical electrical silence can coexist with active motor responses and preserved respiratory drive for many hours. Bladder control increases the incidence of urinary retention after epidural analgesia after paediatric orthopaedic surgery…”

mentioning

confidence: 75%

Protracted cerebral circulatory arrest and cortical electrical silence coexisting with preserved respiratory drive and flexor motor response

Budohoski¹

2012

BJA: British Journal of Anaesthesia

View full text Add to dashboard Cite

“…AL or GL must be cleared within time limit of cerebral anoxia for irreversible brain death that is extremely variable for individuals between five to twenty minutes or so in normothermic ischemic anoxia. 45,46 This short-stipulated time may not be enough for any gas to clear in RH devoid of other venous outlets than PT and without active interference. By the time, symptoms start declaring, events of embolism may have far advanced for our cognitive senses to salvage life.…”

Section: Discussionmentioning

confidence: 99%

Threshing grain of mechanism from chaffy myth of air embolism in laparoscopy - lux et veritas

Kumar

Sudrania

2018

Int Surg J

View full text Add to dashboard Cite

Biomechanical processes involving exact mechanism of air embolism (AE) or gas embolism (GE) in pneumoperitoneum (PP) in operative laparoscopy (OL) causing morbidity and mortality lie in air lock (AL) or gas lock (GL) in right side of heart resulting in traffic jam (TJ) for blood flow in pulmonary tree (PT). This also leads to poorly understood cascade of immunopathological pulmonary reactions. These issues are critically reviewed and discussed to thresh the grain of mechanism from husk of myth of ghost of AE or GE in OL for its dreaded moribund complications. Physics of gas is defined with analysis that venous GE is not exclusive to ambient air (AA) in OL but occurs with CO2, N2O, O2 and other gases also. It is important since use of AA in OL is useful or ostensibly better than CO2 in situations like pregnancy, camps, cardiopulmonary cripples, cirrhotics, war fields, etc and economic needing no cylinders as AA is ubiquitous. Even when gas used was or is CO2 or O2 but blemish is labelled on air for embolism imprudently needing scientific scrutiny.

show abstract

Brain death: time for an international consensus

Cited by 46 publications

References 22 publications

Brainstem death: A comprehensive review in Indian perspective

Brainstem death: A comprehensive review in Indian perspective

Protracted cerebral circulatory arrest and cortical electrical silence coexisting with preserved respiratory drive and flexor motor response

Threshing grain of mechanism from chaffy myth of air embolism in laparoscopy - lux et veritas

Contact Info

Product

Resources

About