The functional asymmetry of the human brain hemispheres (motor, sensory and mental) reflects the difference in the distribution of neuropsychological functions between its right and left hemispheres. Both hemispheres are involved in the implementation of any types of mental activity or regulation of vegetative physiological processes, but each of them provides different aspects of this activity and some processes domination. Persons with left-hemisphere and right-hemisphere thinking differ in the features of perception, analysis, and reproduction of information, which is important in the process of students' educational activities. That is why the aim of this investigation was to conduct a comparative analysis of the types of the brain hemispheres dominance in students of natural and humanities education who study at the biological and philosophical faculties of the Ivan Franko National University of Lviv and proposed methodological approaches for development and activation both (left and right) brain hemispheres. Methods used in the study: determining the coefficient of functional asymmetry of the brain; general scientific (analysis and synthesis), methods of theoretical research (from abstract to concrete). It was shown that most of the student are dominated by the left brain hemisphere but organizing of the educational process needs to use methods of educational activities aimed at the development and activation both (left and right) brain hemispheres.