2024
DOI: 10.1101/2024.05.29.596533
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Brain implantation of tissue-level-soft bioelectronics via embryonic development

Hao Sheng,
Ren Liu,
Qiang Li
et al.

Abstract: The design of bioelectronics capable of stably tracking brain-wide, single-cell, and millisecond-resolved neural activities in the developing brain is critical to the study of neuroscience and neurodevelopmental disorders. During development, the three-dimensional (3D) structure of the vertebrate brain arises from a 2D neural plate1,2. These large morphological changes previously posed a challenge for implantable bioelectronics to track neural activity throughout brain development3–9. Here, we present a tissue… Show more

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