1986
DOI: 10.1016/s0140-6736(86)92145-8
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Brain Lesions Detected by Magnetic Resonance Imaging in Mild and Severe Head Injuries

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Cited by 159 publications
(50 citation statements)
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“…25 MR imaging was first used to investigate TBI in a study of 50 patients, published by Jenkins et al in 1986. 26 Since that initial study was published, several descriptions of MR imaging of lesions in TBI patients have been reported, but few studies exist on the correlation between imaging and outcome.…”
Section: Discussionmentioning
confidence: 99%
“…25 MR imaging was first used to investigate TBI in a study of 50 patients, published by Jenkins et al in 1986. 26 Since that initial study was published, several descriptions of MR imaging of lesions in TBI patients have been reported, but few studies exist on the correlation between imaging and outcome.…”
Section: Discussionmentioning
confidence: 99%
“…There are very few studies examining mechanisms of LOC in rodent TBI models; however, posttraumatic coma has been associated with degree of axonal injury in rodent and human TBI. 18,19 Axonal injury is a prominent feature of CCI 20 but is infrequently detected in the CHI model by APP immunohistochemistry (current study) or by electron microscopy. 12 LOC was significantly increased in a sequential linear/angular acceleration model compared with linear or angular acceleration alone, and sequential injury also significantly increased axonal damage in that study.…”
Section: Discussionmentioning
confidence: 66%
“…This finding as in the case of detection of contusive injuries, may simply reflect the higher sensitivity of MR imaging to these injuries, as previously demonstrated in other studies. [25][26][27][28][29] The time delay between initial CT and follow-up rMRI could also result in increased conspicuity of axonal injury due to interval blossoming. Additionally, DWI and FLAIR imaging may be more sensitive for the detection of diffuse axonal in- shows an occipital fracture with a corresponding fracture seen on the axial T2 TSE sequence (E).…”
Section: Discussionmentioning
confidence: 99%