Pediatric Neuroradiology 2005
DOI: 10.1007/3-540-26398-5_4
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Brain Malformations

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Cited by 31 publications
(33 citation statements)
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“…The range of classic holoprosencephaly includes 3 subtypes in decreasing order of severity: alobar, semilobar, and lobar. [5][6][7] The mildest form of classic holoprosencephaly manifests with partial forebrain and diencephalic union. The hypothalamus is incompletely separated in the mildest of forms of hypothalamic union in all patients with holoprosencephaly in their cohort.…”
Section: Discussionmentioning
confidence: 99%
“…The range of classic holoprosencephaly includes 3 subtypes in decreasing order of severity: alobar, semilobar, and lobar. [5][6][7] The mildest form of classic holoprosencephaly manifests with partial forebrain and diencephalic union. The hypothalamus is incompletely separated in the mildest of forms of hypothalamic union in all patients with holoprosencephaly in their cohort.…”
Section: Discussionmentioning
confidence: 99%
“…Unlike CM-II or CM-III, there is no relation to neural tube closure defects. 16 Chiari malformation Type I may result from developmental hypoplasia of the occipital somites creating a congenitally small posterior fossa. This reduced posterior fossa volume may in turn result in compression and herniation of the cerebellar tonsils.…”
Section: Discussionmentioning
confidence: 99%
“…In humans, it increases during ontogenesis from the smooth initial brain surface with values close to 1.0 towards the heavily convoluted adult brain surface with values between 2.5 and 3.043. Lissencephalic brains have smaller gyrification indices2; Polymicrogyric brains have larger gyrification indices3. To quantify the degree of cortical folding for varying cortical growth rates and varying cortical thicknesses, we determine the gyrification index semi-automatically by contour tracing.…”
Section: Methodsmentioning
confidence: 99%