“…Deep Learning (DL) methods are the state-of-the-art approach for tackling automatic medical image segmentation tasks, with the U-Net [5] being the most widely adopted network variation [6]. Currently, the DL based medical image segmentation literature focuses predominantly on network architecture and architectural modifications, such as the integration of residual, dense, or inception blocks, for achieving performance improvements with evaluation commonly conducted on a single dataset or restricted number of datasets [7,8,9,10,11,12,13,14,15]. However, in addition to network architecture, DL based automatic segmentation performance depends on further network training pipeline components and hyperparameters, for example, image resampling strategy, input image patch size, augmentation strategy etc.…”