Brain natriuretic peptide concentration in pericardial fluid is independently associated with atrial fibrillation after off-pump coronary artery bypass surgery

Abstract

Our results suggested that pericardial fluid brain natriuretic peptide concentration is independently associated with the development of atrial fibrillation after off-pump coronary artery bypass grafting.

Preoperative plasma brain natriuretic peptide level is an independent predictor of postoperative atrial fibrillation following off-pump coronary artery bypass surgery

“…These include low ejection fraction and the infl uence of cardioplegic arrest [5,[10][11][12]. On the other hand, not much information is available on the independent predictors of postoperative AF following OPCAB [7][8][9]13,14]. Anastomoses of the ramus medianus, and some other perioperative factors, including BNP level in pericardial fl uid, intraoperative fl uid balance, intraoperative core temperature, and postoperative cardiac index have been reported as predictors eters [24].…”

“…Consequently, the time required by patients with postof AF following OPCAB [7][8][9]. Biomarkers indicating infl ammatory status, such as baseline C-reactive protein level, postoperative elevation of interleukin-6, and white blood cell count have been reported as independent predictors of AF following both conventional CABG and OPCAB [13][14][15].…”

“…Hakala et al [36] and Nakamura et al [7] reported that the preoperative BNP level was not an independent predictor of postoperative AF following CABG. This difference from our fi ndings may be partly explained by the fact that the preoperative BNP level in our patients was more elevated than the levels in their patients, indicating that the LV function in their patients was not as impaired as that in our patients.…”

“…Several factors, including low ejection fraction, and cardiac arrest have been reported as predictors of postoperative AF following conventional CABG [5,[10][11][12]. On the other hand, some perioperative factors have also been reported to be predictors of postoperative AF following OPCAB [7,8,13]. Biomarkers indicating the infl ammatory status of the patient, such as baseline C-reactive protein level, postoperative interleukin-6 level, and white blood cell count have been reported as independent predictors following conventional CABG and OPCAB [14,15].…”

“…However, controversy still remains as to whether OPCAB can reduce the incidence of postoperative AF [2][3][4][5]. Although a recent metaanalysis showed OPCAB signifi cantly reduced the incidence of postoperative AF compared with conventional CABG [6], the incidence of postoperative AF following OPCAB has been reported to remain high, at 21%-32% [2,3,[7][8][9]. Several factors, including low ejection fraction, and cardiac arrest have been reported as predictors of postoperative AF following conventional CABG [5,[10][11][12].…”