Brain neoplasms: epidemiology, diagnosis, and prospects for cost-effective imaging

Hutter, Alf; Schwetye, Katherine E.; Bierhals, Andrew J.; McKinstry, Robert C.

doi:10.1016/s1052-5149(03)00016-9

Cited by 65 publications

(32 citation statements)

References 67 publications

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“…15 Only one economic model has been published in an investigation of tumour in children with headache. 16 For high-risk groups, defined as a 4% level of risk, MRI yielded a cost per QALY that was over twice the currently accepted guidelines.…”

Section: At What Level Of Risk Of Brain Tumour Should Imaging Be Undementioning

confidence: 99%

Imaging patients with suspected brain tumour: guidance for primary care

Kernick

Ahmed²,

Bahra

et al. 2008

Br J Gen Pract

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The number of referrals by primary care practitioners to secondary care neurology services, particularly for headache, may be difficult to justify. Access to imaging by primary care practitioners could avoid referral without compromising patient outcomes, but the decision to refer is based on a number of complex factors. Due to the paucity of rigorous evidence in this area, available data are combined with expert opinion to offer support for GPs. The study suggests management for three levels of risk of tumour: red flags >1%; orange flags 0.1-1%; and yellow flags <0.1% but above the background population rate of 0.01%. Clinical presentations are stratified into these three groups. Important secondary causes of headache where imaging is normal should not be overlooked, and normal investigation does not eliminate the need for follow-up or appropriate management of headache.

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Section: At What Level Of Risk Of Brain Tumour Should Imaging Be Undementioning

confidence: 99%

Imaging patients with suspected brain tumour: guidance for primary care

Kernick

Ahmed²,

Bahra

et al. 2008

Br J Gen Pract

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show abstract

“…In this series, MRI was obtained before surgery in 92% of the patients: this compares with a 75% value for the 1997-2001 accrual period of the present series. The majority of the published reports consider MRI as the imaging procedure of choice for glioma patients (15,16) and CT a complementary procedure. Therefore, in this relatively large sample of the centers caring for glioma patients in Italy, there is room for improvement in the use of imaging for staging and postsurgical evaluation.…”

Section: Pattern-of-practice Analysismentioning

confidence: 99%

Patterns of practice and survival in a retrospective analysis of 1722 adult astrocytoma patients treated between 1985 and 2001 in 12 Italian radiation oncology centers

Magrini

Ricardi

Santoni

et al. 2006

International Journal of Radiation Oncology*Biology*Physics

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“…The rise in the prevalence of cancer consequently increases the population at risk for developing brain metastases, with the reported annual incidence estimated between 98,000 and 170,000 [2][3][4]. Brain metastases can lead to rapid deterioration in quality of life (QOL) brought on by progressive neurologic deficits which can be a daunting challenge for family caregivers [5].…”

Section: Introductionmentioning

confidence: 99%