Brain oxygenation monitoring during neonatal resuscitation of very low birth weight infants

Fuchs, Hans; Lindner, Wolfgang; Buschko, Anja; Almazam, M; Hummler, Helmut; Schmid, Manuel

doi:10.1038/jp.2011.110

Cited by 67 publications

(51 citation statements)

References 45 publications

(60 reference statements)

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“…Briefly, that study included c StO 2 , SpO 2 and heart rate measurements of 51 infants of 27.8 ± 2.6 weeks' gestational age during transition after birth, and most infants had been stabilized using CPAP or sustained inflations at FiO 2 0.4. An identical device, sensors and sensor location were used in both studies [3]. …”

Section: Methodsmentioning

confidence: 99%

“…Fractional tissue oxygen extraction (FTOE) was calculated using the formula: (SpO 2 - c StO 2 )/SpO 2 [15]. c StO 2 values of healthy term infants were compared to c StO 2 of the VLBW infants described previously [3]. Briefly, that study included c StO 2 , SpO 2 and heart rate measurements of 51 infants of 27.8 ± 2.6 weeks' gestational age during transition after birth, and most infants had been stabilized using CPAP or sustained inflations at FiO 2 0.4.…”

Section: Methodsmentioning

confidence: 99%

“…We recently reported c StO 2 in VLBW infants after birth [3,9]. We were interested to compare the data of these infants that required assistance for stabilization to values from normal healthy term infants.…”

Section: Introductionmentioning

confidence: 99%

“…This technique may provide useful information for the prevention of brain damage during transition from fetal to neonatal life [3,4]. Data on cerebral oxygenation during the transition of term and preterm infants have become available recently, including measurement of c StO 2 in term infants after spontaneous delivery [5,6], in term infants after caesarean section (CS) [7,8] and, more recently, in very-low-birth-weight infants (VLBW) [3,9]. Differences in absolute values of c StO 2 appear to exist between these groups.…”

Section: Introductionmentioning

confidence: 99%

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Cerebral Near-Infrared Spectroscopy during Transition of Healthy Term Newborns

et al. 2013

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Background: Values of regional cerebral tissue oxygen saturation (cStO₂) have been described during transition of term and preterm infants after birth. However, use of different devices precludes comparison of measurements. Objective: To measure cStO₂ during transition of term infants using a calibrated 4-wavelength laser light source near-infrared spectroscopy oximeter (FORE-SIGHT) to obtain data that allow comparison with cStO₂ of very-low-birth-weight (VLBW) infants using this oximeter and with cStO₂ of term infants using different oximeters. Methods:cStO₂ (FORE-SIGHT oximeter), preductal arterial oxygen saturation and heart rate were measured in 46 healthy term infants (n = 20 spontaneous delivery, n = 22 caesarean section, n = 4 assisted vaginal delivery) during the first 10 min after delivery. Results: The median (interquartile range) cStO₂ at 2 min after birth was 42% (39-46) after spontaneous delivery, 42% (30-52) after caesarean section and 36% (20-53) after assisted vaginal delivery (no difference between groups). In association with increasing arterial oxygen saturation and heart rate, cStO₂ increased continuously and reached a steady state approximately 8 min after birth of 62-77% (interquartile range) in all three groups. Conclusions: Healthy term newborns had similar cStO₂ changes from 2 min after birth regardless of the mode of delivery. cStO₂ of healthy term infants was lower than cStO₂ of VLBW infants during transition. cStO₂ values as measured by the FORE-SIGHT oximeter seem in the range of values as measured by the NIRO 300 oximeter. They were lower than values as measured by the INVOS 5100 oximeter.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Cerebral Near-Infrared Spectroscopy during Transition of Healthy Term Newborns

et al. 2013

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“…Показано, что у детей с очень низкой мас-сой тела уже к 7-й минуте жизни сатурация кисло-рода в ткани мозга составляет 61-84 % [15]. Ме-тод применяется также для выявления изменений церебральной оксигенации в связи с колебаниями системной гемодинамики у больных недоношен-ных детей.…”

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Сerebral oxymetry in neonatology

Evsyukova

2017

Pediatr (SPb)

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The frequency of disturbance the functional development of newborn brain after intrauterine and birth asphyxia determines the necessity the finding objective methods of timely diagnosis the alteration of brain oxygenation for the target therapy. During last years the special attention of investigators was attracted to use for this purpose in newborns the noninvasive, informative and portable method near-infrared spectroscopy (NIRS). Cerebral oxymetry successfully used for estimation brain circulation of the blood and blood volume in the brain vessels with combination constant monitoring blood pressure. This review outlines the basic principles, advantages NIRS technology in clinical studies brain oxygenation in healthy full term and premature newborns and also after asphyxia, vacuum extraction and cesarean section. Monitoring brain oxygenation in newborns which received cooling after heavy asphyxia permits during first 10 hours after birth to prognosis unfavorable outcome or fix the further strategy of treatment cerebral ischemia. Presented clinical use this method for treatment premature newborns with respiratory distress and circulatory insufficiency. It may help to determine the optimal target oxygen saturation. It is alsow useful monitoring during intensive therapy of extremely preterm neonates, due to the risk of impaired cerebral blood flow auto regulation in these patients. Indicated the perspectives of cerebral oxymetry in neonato logy for new diagnostic, treatment and prophylactic perinatal CNS damage.

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Regional pulmonary oxygen saturations in late preterm and term infants with respiratory distress at birth

Yasa,

Kersin,

Cetinkaya

et al. 2024

Pediatric Pulmonology

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BackgroundMeasurement of regional pulmonary oxygen saturation by near‐infrared spectroscopy is a novel monitorization method. This study aimed to determine the early regional pulmonary oxygen saturations in neonates with respiratory distress.MethodsThis observational study was conducted at the delivery room in infants above 35 weeks of gestation who developed respiratory distress immediately after birth. Preductal oxygen saturation (Covidien Nellcor®) and regional oxygen saturations of both apical (raSO2) and basal regions (rbSO2) of right lung were measured (Covidien INVOS®) within the first 15 min of life and compared to those of healthy neonates.ResultsOf the 165 infants included to the study, 15 were late preterm and 55 developed respiratory distress. Infants with respiratory distress had significantly lower gestational age and birth weight. Regional pulmonary oxygenations at both apex and basal lung areas were positively correlated with SpO2 in all infants. The rbSO2 was significantly lower than raSO2 until 10th minute of life regardless of respiratory distress. The fractionized tissue oxygen extraction of both apical and basal lung areas was significantly higher in infants with respiratory distress until 5th minute of life.ConclusionThis study is one of the pioneer studies evaluating the early pulmonary oxygenation values of infants with respiratory distress. Oxygenation of apical lung regions are better than basal areas. Higher fractionized tissue oxygen extraction showed the impaired pulmonary perfusion in infants with respiratory distress.

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Brain oxygenation monitoring during neonatal resuscitation of very low birth weight infants

Cited by 67 publications

References 45 publications

Cerebral Near-Infrared Spectroscopy during Transition of Healthy Term Newborns

Cerebral Near-Infrared Spectroscopy during Transition of Healthy Term Newborns

Сerebral oxymetry in neonatology

Regional pulmonary oxygen saturations in late preterm and term infants with respiratory distress at birth

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