Brain stem tuberculoma presenting with isolated ocular motility abnormality: A series of two cases and review of literature

Sharma, Kumudini; Kanaujia, Vikas; Jaiswal, Sushila; Jain, Abhishek; Kumar, Sheo; Srivastava, Arun Kumar; Jaiswal, Awadhesh Kumar

doi:10.4103/0974-620x.94782

Cited by 8 publications

(1 citation statement)

References 6 publications

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“…[ 2 ] Isolated brain stem tuberculoma is rare and constitutes 5% of all intracranial tuberculomas in endemic areas. [ 3 4 ] Clinical manifestations can be varied depending largely on their location and number. [ 5 6 7 8 ] Patients can present with signs of raised intracranial pressure or focal neurological deficits such as cranial nerve palsy and motor and sensory symptoms.…”

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Weber syndrome secondary to brain stem tuberculoma

Parija

Lalitha

Naik

2018

Indian J Ophthalmol

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This case report describes a rare presentation of presumed brain stem tuberculoma in a 28-year-old male who presented with acute onset of third cranial nerve palsy with contralateral hemiparesis (Weber syndrome) and upgaze palsy. Isolated midbrain tuberculoma is rare, presenting with varied clinical manifestations and radiological findings posing as a diagnostic dilemma. Weber syndrome is commonly caused by midbrain infarct secondary to occlusion of branches of the posterior cerebral artery and rarely from a tuberculoma. The patient is a case of disseminated tuberculosis with granuloma in midbrain causing pressure effect, thereby presenting with features consistent with Weber syndrome and upgaze palsy. The patient had good recovery with antitubercular treatment and systemic steroids.

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confidence: 99%

Weber syndrome secondary to brain stem tuberculoma

Parija

Lalitha

Naik

2018

Indian J Ophthalmol

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Imaging Findings of Tuberculosis of the Cranial and Peripheral Nerves

Gupta

Saini

Gupta

2017

Tuberculosis of the Central Nervous System

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Isolated brainstem tuberculomas

et al. 2017

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Intracranial tuberculomas may present with or without meningitis. A high index of suspicion is essential, especially in endemic areas. A combination of clinical symptoms, investigations, and imaging features help in coming to a diagnosis. Biopsy of a brainstem lesion is fraught with complications. Antitubercular therapy has a very good prognosis, though the duration of therapy required may be longer.

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Brain stem tuberculoma presenting with isolated ocular motility abnormality: A series of two cases and review of literature

Cited by 8 publications

References 6 publications

Weber syndrome secondary to brain stem tuberculoma

Weber syndrome secondary to brain stem tuberculoma

Imaging Findings of Tuberculosis of the Cranial and Peripheral Nerves

Isolated brainstem tuberculomas

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