Brain tumours and mobile phones? To the Editor

Borghesi, Joanna L

doi:10.5694/j.1326-5377.1998.tb140169.x

Cited by 1 publication

(1 citation statement)

References 3 publications

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“…A considerable debate has arisen about potential health hazards of mobile phones, and the wide spread use of modern telecommunication devices has sparked public concern about the safety of its use (for a recent debate, see Rouse [1997]; Armstrong and Jong [1998]; Ban [1998]; Borghesi [1998]; Davidson [1998]; Frey [1998]; Hocking [1998]; McWhirter and Dobson [1998]; Russell [1998]; Samuels and Wise [1998]).…”

Section: Introductionmentioning

confidence: 99%

No mutagenic or recombinogenic effects of mobile phone fields at 900 MHz detected in the yeastSaccharomyces cerevisiae

Gos¹,

Eicher

Kohli³

et al. 2000

Bioelectromagnetics

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Both actively growing and resting cells of the yeast Saccharomyces cerevisiae were exposed to 900-MHz fields that closely matched the Global System for Mobile Communication (GSM) pulsed modulation format signals for mobile phones at specific absorption rates (SAR) of 0.13 and 1.3 W/kg. Two identical anechoic test chambers were constructed to perform concurrent control and test experiments under well-controlled exposure conditions. Using specific test strains, we examined the genotoxic potential of mobile phone fields, alone and in combination, with a known genotoxic compound, the alkylating agent methyl methansulfonate. Mutation rates were monitored by two test systems, a widely used gene-specific forward mutation assay at CAN1 and a wide-range assay measuring the induction of respiration-deficient (petite) clones that have lost their mitochondrial function. In addition, two further assays measured the recombinogenic effect of mobile phone fields to detect possible effects on genomic stability: First, an intrachromosomal, deletion-formation assay previously developed for genotoxic screening; and second, an intragenic recombination assay in the ADE2 gene. Fluctuation tests failed to detect any significant effect of mobile phone fields on forward mutation rates at CAN1, on the frequency of petite formation, on rates of intrachromosomal deletion formation, or on rates of intragenic recombination in the absence or presence of the genotoxic agent methyl methansulfonate.

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