Brainstem Acoustic Evoked Responses: Maturational Aspects from Cochlea to Midbrain

Lauffer, Heinz; Wenzel, D.

doi:10.1055/s-2008-1071461

Cited by 15 publications

(8 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…e C ! x ) was chosen based on (1) fi ndings of repeated measures ANOVA analyses, (2) the common use of this function to describe biological processes, (3) the use of exponential functions to describe developmental changes in the acoustically evoked ABR in normally hearing children [Eggermont and Salamy, 1988;Lauffer and Wenzel, 1990;Ponton et al, 1992Ponton et al, , 1996a, thereby allowing comparisons with those analyses, (4) the ability to calculate a time constant (1/C) describing the time course of change, and (5) the assumption that the response does reach a state of maturity (the asymptote, A, of the exponential function provides a prediction of this value). The single exponent curves model one overall process of change.…”

Section: Analysesmentioning

confidence: 99%

“…Values obtained from young children can be fi t to a decreasing exponential function where the asymptote equals the adult values and a developmental time constant can be calculated. By evaluating ABR parameters in this way, it has been suggested that the human auditory brainstem reaches maturation by approximately 1-3 years of age [Eggermont and Salamy, 1988;Gorga et al, 1989;Lauffer and Wenzel, 1990]. For cochlear implant subjects, however, the asymptote of the mature electrically evoked system is not clear.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An Evoked Potential Study of the Developmental Time Course of the Auditory Nerve and Brainstem in Children Using Cochlear Implants

Gordon

Papsin²,

Harrison³

2006

Audiol Neurotol

View full text Add to dashboard Cite

Central auditory responses to electrical stimulation from a cochlear implant were studied in 75 pre-lingually deafened children and 11 adults. Electrically evoked auditory brainstem response (EABR) latencies significantly decreased with duration of cochlear implant use and were not significantly affected by the age at implant activation. Significant decreases in early latency waves and interwaves occurred within the first 1–2 months of implant use, whereas longer term changes (6–12 months) were found for eV and eIII-eV, which measure activity in the more rostral brainstem. Comparisons to acoustically evoked auditory brainstem response (ABR) in children with normal hearing suggested shorter interwave EABR latencies, reflecting either distinct neural generators or increased neural synchrony, but similar rates of change in the later latency eV and eIII-eV with time in sound. In sum, normal-like development of the rostral auditory brainstem is promoted by cochlear implant use in children of a wide range of ages.

show abstract

Section: Analysesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

An Evoked Potential Study of the Developmental Time Course of the Auditory Nerve and Brainstem in Children Using Cochlear Implants

Gordon

Papsin²,

Harrison³

2006

Audiol Neurotol

View full text Add to dashboard Cite

show abstract

“…Various parameters of the ABRs are known to change as a function of age or stimulus intensity, thus providing a useful tool to evaluate hearing threshold [Hecox and Galambos, 1974;Roncagliolo et al, 1983;Thivierge and Coté, 1990] and maturity or neurological status of auditory brainstem structures [Salamy et al, 1975;Starr and Hamilton, 1976;Stockard and Rossiter, 1977;Starr, 1978;Mochizuki et al, 1982;Lauffer and Wenzel, 1990;Roncagliolo et al, 1994]. During development the several waves of ABRs progressively increase in amplitude and decrease in both absolute and interpeak latencies (IPLs) [Salamy and McKean, 1976;Starr et al, 1977;Mochizuki et al, 1982;Salamy et al, 1982;Vles et al, 1987;LinaGranade et al, 1993;Ferber-Viart et al, 1996;Roncagliolo et al, 1998].…”

Section: Introductionmentioning

confidence: 99%

“…These features reveal a developing synchrony in the discharges of component fibers and an increase in their conduction velocity due to myelination. Thus ABRs can be considered as an index of CNS maturation [Lauffer and Wenzel, 1990;Jiang et al, 1993;Ichiyama et al, 1995;Roncagliolo et al, 1998]. …”

Section: Introductionmentioning

confidence: 99%

Progressive Deterioration of Central Components of Auditory Brainstem Responses during Postnatal Development of the Myelin Mutant <i>taiep</i> Rat

Roncagliolo

Benítez²,

Eguíbar³

2000

Audiol Neurotol

View full text Add to dashboard Cite

Auditory brainstem responses (ABRs) were evaluated during the postnatal development (P10–P180) of taiep rats, neurological mutants characterized by early abnormal myelin development and subsequent demyelination of the CNS. The disorder is produced by an autosomal recessive mutation trait that affects the oligodendrocytes but not the Schwann cells. After onset of ABRs (P12–P14), taiep rats and their nonaffected heterozygous littermates that served as controls showed a similar pattern of maturation for wave I. The central waves (In–IV) showed significantly longer latencies in the mutants. By P60–P180, the later waves (III and IV) were frequently difficult to discern. From the onset of ABRs, the interpeak latency I–IV, corresponding to the central conduction time (CCT) of the auditory pathway, showed in taiep rats significantly longer values than controls. After an initial reduction, proportional to that of control rats, the CCT value increased progressively during the second month of the mutants’ lives. The electrophysiological results of the present study strongly support the hypothesis that mutation in the taiep rat impairs neuromaturation of the central auditory pathway in the brainstem by affecting the myelination process in the CNS.

show abstract

“…Die Eltern [7], gegebenenfalls auch das Kind selbst [5] sollten darauf hingewiesen werden, bei plötzlicher Akzeptanzveränderung baldmöglichst eine aktuelle Kontrolle zu veranlassen: Neben Hörgerätemängeln, Cerumen, otoplastikbedingten Reaktionen im äuße-ren Gehörgang und die im Kindesalter besonders häufigen mittelohrbedingten Hörstörungen wäre hierbei eine In unserem Patientengut war eine nicht korrekte Otoplastikform der Grund für 9% aller Mängel, wobei ein Hörschwellenänderung, etwa im Sinne einer Nachreifung der Hörbahn oder einer Progredienz auszuschließen [8,11,13,15].…”

Section: Introductionunclassified

Qualitätskontrolle der kindlichen Hörgeräteversorgung

Niehaus

Schroff

Kruse

1997

HNO

View full text Add to dashboard Cite

Specific hearing aid selection and careful fitting are essential for successful rehabilitation of hearing-impaired children. For this reason the different hearing aid types prescribed, the type and frequency of hearing aid insufficiencies reported and the effectiveness and regularity of our follow-ups were studied evaluating 253 followup exams in 39 children (71 ears) suffering of a sensorineural hearing loss, including all degrees, supplied with a behind-the-ear hearing aid. Most of the devices had been prescribed outside our department on an initial trial basis. After critical evaluation, the number of hearing aid types was reduced from 33 to 23 when corresponding devices failed to match well with the degrees and types of hearing losses present. A further decrease in hearing aid types could not be achieved as a consequence of many being already end-prescribed. Insufficiencies (n = 222) were found in 60% of the hearing aid evaluations: 59% involved dynamic hearing aid adjustments requiring better amplification (37%), distortion (18%) and dynamics (4%). Additionally, 16% affected hearing aid function and another 16% form (9%) and material (4%) of the otoplasty and the tube (3%). The last 9% of the deficiencies concerned the potentiometer cap: it hadn't been fitted in about half of the cases and had been lost in the other half despite being needed. Routine followup evaluations of the hearing aids occurred regularly in 76% of the cases with an effectiveness of 73%. Our results confirm the importance and necessity for pedaudiologic qualitative hearing aid controls in children.

show abstract

Brainstem Acoustic Evoked Responses: Maturational Aspects from Cochlea to Midbrain

Cited by 15 publications

References 11 publications

An Evoked Potential Study of the Developmental Time Course of the Auditory Nerve and Brainstem in Children Using Cochlear Implants

An Evoked Potential Study of the Developmental Time Course of the Auditory Nerve and Brainstem in Children Using Cochlear Implants

Progressive Deterioration of Central Components of Auditory Brainstem Responses during Postnatal Development of the Myelin Mutant <i>taiep</i> Rat

Qualitätskontrolle der kindlichen Hörgeräteversorgung

Contact Info

Product

Resources

About