Branch retinal artery occlusion in a patient with one eye. Laser Nd:YAG approach

Pérez-Larraya, A.M. Solans; Ortega-Molina, J.M.; Salgado-Miranda, A.D.; García-Serrano, J.L.

doi:10.1016/j.oftale.2016.04.012

Cited by 4 publications

(1 citation statement)

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“…Traditional treatment modalities include ocular massage, anterior chamber paracentesis, intraocular pressure-lowering medications, and vasodilators, all of which are relatively ineffective [6,7]. In recent years, treatment modalities have been developed including delivery of thrombolytic agents by surgical approaches [8,9] and the removal of embolism by the Nd: YAG laser [10]. Currently, digital subtraction angiography (DSA)-guided superselective ophthalmic artery thrombolysis or selective carotid intervention remains the preferred treatment method for CRAO [11–15].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Ophthalmic Artery Branch Retrograde Intervention in the Treatment of Central Retinal Artery Occlusion (CRAO)

et al. 2017

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BackgroundCentral retinal artery occlusion (CRAO) is the occlusion of the central retinal artery resulting in retinal infarction and acute vision loss. Digital subtraction angiography (DSA)–guided superselective ophthalmic artery or selective carotid thrombolysis remains the preferred treatment method for CRAO. This study aimed to evaluate the safety and clinical efficacy of the novel ophthalmic artery branch retrograde thrombolytic intervention for CRAO.Material/MethodsFifty patients with monocular CRAO were enrolled, including 28 males and 22 females (mean age: 55.7±2.3 years). The patients were randomly divided into two groups for thrombolysis with urokinase (400,000 U) and papaverine (30 mg) by either ophthalmic artery branch retrograde intervention (group A, n=26) or superselective ophthalmic artery/selective carotid intervention (group B, n=24). There was no significant difference in age (P=0.58), gender ratio (P=0.49), and time to onset (P=1.00) between the two groups. The adverse reactions and clinical efficacy were evaluated by postoperative DSA, fundus fluorescein angiography (FFA), and visual acuity tests.ResultsNo serious complications, abnormal eye movement, or vitreous hemorrhage occurred in either group. DSA showed that group A had an effective rate (92.30%) comparable to that of group B (100%, χ2=2.08, P=0.25). FFA suggested that both groups had similar treatment efficacy (χ2=3.09, P=0.21). Visual acuity tests also confirmed a similar efficacy of the two intervention approaches (χ2=0.25, P=0.88).ConclusionsThe developed novel ophthalmic artery branch retrograde intervention is highly effective and safe for CRAO, and may be a superior method compared with the conventional approach.

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