Branchial cleft cysts Histologic and immunohistochemical aspects

Ninomiya, Tomihisa; Hosaka, Matsuji; Higashiyama, Hidetoshi; Kurenuma, Shuji; Mori, Masahiko

doi:10.1016/s0065-1281(89)80059-5

Cited by 7 publications

(4 citation statements)

References 21 publications

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“…Pathological examination shows that the fi stula lining is composed of benign squamous and/or columnar epithelia [9] . In 3 of our cases, the tracts were lined by columnar epithelia, whereas the rest by squamous epithelia.…”

Section: Discussionmentioning

confidence: 99%

Second Branchial Anomalies in Children

Karabulut

Sönmez²,

Türkyılmaz³

et al. 2005

ORL

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Aim: The aim of this study was to evaluate the data of our patients who had been treated for second branchial anomalies in the last 10 years. Here we report our clinical experience in second branchial anomalies with a review of the literature. Patients and Methods: We evaluated retrospectively the data of 14 patients, who had been operated on between 1994 and 2004 for second branchial anomalies, in relation to age, sex, complaint at application, diagnostic test, surgical procedures and histopathologic findings. Results: The mean age of the patients (8 female, 6 male) was 5.3 years (range = 1.5–16). The anomalies were usually located on the left side of the neck (n = 6). There were only 3 cases with bilateral anomalies. The majority of the lesions were sinuses (93%). The most frequent clinical feature was the presence of persistent discharge from an external (cutaneous) orifice. All lesions were excised by performing a second step ladder incision. Eight of the lesions were removed under the guidance of 3/0 polypropylene suture. No postoperative complication or recurrence was observed during the follow-up period. Conclusions: Second branchial arches anomalies are the most common branchial anomalies. Sinuses are more frequently encountered in children. Definitive treatment for these lesions is surgical excision. A polypropylene suture can be inserted into the tract as a guide to prevent incomplete excision.

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Section: Discussionmentioning

confidence: 99%

Second Branchial Anomalies in Children

Karabulut

Sönmez²,

Türkyılmaz³

et al. 2005

ORL

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“…Subepithelial lymphoid tissue from mesodermal differentiation is described in a large number of such lesions, particularly the cystic ones (30% and 90% of cases in two series). 10 Origination of the epithelial and histiocytic components of the aspirate from other epithelial structures of the region, such as the palatine tonsil or salivary duct lesion, was also considered, but it was dismissed because of the direction of the aspiration and weak cytokeratin immunostaining, not favoring salivary ductal origin. In contrast, epithelium from salivary ducts and their lesions in this study showed intense staining for cytokeratin.…”

Section: Incidental Sampling Of Branchial Remnantsmentioning

confidence: 99%

Incidental sampling of branchial remnants: A potential source of error in fine-needle aspiration of neck lesions—a case report

Zaharopoulos

2000

Diagn. Cytopathol.

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“…Subepithelial lymphoid tissue from mesodermal differentiation is described in a large number of such lesions, particularly the cystic ones (30% and 90% of cases in two series). 1,5,10 Ninomiya et al, 10 having investigated the immunohistologic characteristics of the branchial epithelium in cases of branchial cystic anomalies, reported that variable molecular weight cytokeratin immunostaining was confined primarily to the keratinized layer of the squamous epithelium whenever present, while the immature underlying portion remained unstained or very weakly stained. In contrast, epithelium from salivary ducts and their lesions in this study showed intense staining for cytokeratin.…”

Section: Incidental Sampling Of Branchial Remnantsmentioning

confidence: 99%

“…In contrast, epithelium from salivary ducts and their lesions in this study showed intense staining for cytokeratin. 10 Origination of the epithelial and histiocytic components of the aspirate from other epithelial structures of the region, such as the palatine tonsil or salivary duct lesion, was also considered, but it was dismissed because of the direction of the aspiration and weak cytokeratin immunostaining, not favoring salivary ductal origin. We presume that since the anomaly was not detected by tissue exploration down to the carotid sheath, it consisted of a lesion neighboring the pharynx, such as an internal sinus (pharyngeal pouch defect), probably with a luminal dilatation or microcyst formation, suggested by the aspiration of a fair number of histiocytes mingling with the epithelial material.…”

Section: Incidental Sampling Of Branchial Remnantsmentioning

confidence: 99%

Incidental sampling of branchial remnants: A potential source of error in fine-needle aspiration of neck lesions?a case report

Zaharopoulos

2000

Diagn. Cytopathol.

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Remnants of the branchial apparatus can produce lesions in the head and neck region in later life, often amenable to fine‐needle aspiration (FNA) diagnosis. Yet such remnants or rudimentary lesions can remain clinically undetected and can later interfere with the cytologic interpretation of other deep lesions of the neck, as the present case demonstrates. In this case the lesion, which by a subsequent resection turned out to be a neurilemmoma, had been adequately sampled by the FNA, yet the cytologic diagnosis was sidetracked by the presence in the specimen of immature squamous epithelial tissue fragments and other elements (multinucleated histiocytes, calcifications), on the basis of which the diagnosis of an epithelial lesion, likely malignant, was made. The neck surgery and a preceding endoscopic examination of the mouth, pharynx, and larynx did not identify such a lesion, but a detailed microscopic examination of the fibroadipose tissue between the tumor and the peripharyngeal region revealed the presence of epithelial microfragments with morphology partly corresponding to that of the FNA cytology, highly indicative of a branchiogenic lesion in the peripharyngeal region. The basic embryology of the branchial apparatus resulting in such defects is presented, as well as tentative guidelines for recognizing material deriving from accidental sampling of such lesions during FNA investigations of deep‐seated masses of the neck. Diagn. Cytopathol. 2000;22:157–160. © 2000 Wiley‐Liss, Inc.

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Branchial cleft cysts Histologic and immunohistochemical aspects

Cited by 7 publications

References 21 publications

Second Branchial Anomalies in Children

Second Branchial Anomalies in Children

Incidental sampling of branchial remnants: A potential source of error in fine-needle aspiration of neck lesions—a case report

Incidental sampling of branchial remnants: A potential source of error in fine-needle aspiration of neck lesions?a case report

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