Brassinazole resistant 1 (BZR1)-dependent brassinosteroid signalling pathway leads to ectopic activation of quiescent cell division and suppresses columella stem cell differentiation

Lee, Hak Soo; Kim, Yoon; Pham, Giang; Kim, Ju Won; Song, Jae-Young; Lee, Yew; Hwang, Yong-sic; Roux, Stanley J.; Kim, Soo Hwan

doi:10.1093/jxb/erv316

Cited by 54 publications

(44 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is important to note that BRI1 might also activate other downstream components besides BES1. For example, one potential downstream target could be the transcription factor BZR1, which has been shown to promote autonomous QC division when activated ( Chaiwanon and Wang, 2015 ; Lee et al, 2015 ). Interestingly, in the bri1 background lines, we detected an increase in QC division frequency upon BL application ( Fig.…”

Section: Discussionmentioning

confidence: 99%

Paracrine brassinosteroid signaling at the stem cell niche controls cellular regeneration

Lozano-Elena

Planas-Riverola

Vilarrasa-Blasi

et al. 2018

Journal of Cell Science

View full text Add to dashboard Cite

Stem cell regeneration is crucial for both cell turnover and tissue healing in multicellular organisms. In Arabidopsis roots, a reduced group of cells known as the quiescent center (QC) act as a cell reservoir for surrounding stem cells during both normal growth and in response to external damage. Although cells of the QC have a very low mitotic activity, plant hormones such as brassinosteroids (BRs) can promote QC divisions. Here, we used a tissue-specific strategy to investigate the spatial signaling requirements of BR-mediated QC divisions. We generated stem cell niche-specific receptor knockout lines by placing an artificial microRNA against BRI1 (BRASSINOSTEROID INSENSITIVE 1) under the control of the QC-specific promoter WOX5. Additionally, QC-specific knock-in lines for BRI1 and its downstream transcription factor BES1 (BRI1-EMS-SUPPRESOR1) were also created using the WOX5 promoter. By analyzing the roots of these lines, we show that BES1-mediated signaling cell-autonomously promotes QC divisions, that BRI1 is essential for sensing nearby inputs and triggering QC divisions and that DNA damage promotes BR-dependent paracrine signaling in the stem cell niche as a prerequisite to stem cell replenishment.

show abstract

Section: Discussionmentioning

confidence: 99%

Paracrine brassinosteroid signaling at the stem cell niche controls cellular regeneration

Lozano-Elena

Planas-Riverola

Vilarrasa-Blasi

et al. 2018

Journal of Cell Science

View full text Add to dashboard Cite

show abstract

“…For example, root branching patterns (number and rates) were significantly different between seed size classes. Root branching is a key component of root architecture, a character more closely controlled by gene action (Svistoonoff et al, 2007; Thomann et al, 2009), than by resource supply. In addition, the preferential allocation of reserves to the taproot in the small seeded group suggests that the genetic control of developmental and morphological characteristics was very similar within each seed size group.…”

Section: Discussionmentioning

confidence: 99%

Maternal Effects on Seed and Seedling Phenotypes in Reciprocal F1 Hybrids of the Common Bean (Phaseolus vulgaris L.)

et al. 2017

View full text Add to dashboard Cite

Maternal control of seed size in the common bean provides an opportunity to study genotype-independent seed weight effects on early seedling growth and development. We set out to test the hypothesis that the early heterotrophic growth of bean seedlings is determined by both the relative amount of cotyledon storage reserves and the genotype of the seedling, provided the hybrid genotype could be fully expressed in the seedlings. The hypothesis was tested via comparison of seed weight and seedling growth phenotypes of small-seeded (wild, ~0.10 g) and large-seeded (landrace, ~0.55 g) parents and their reciprocal F1 hybrids. Akaike's Information Criteria were used to estimate growth parameters and identify the phenotypic model that best represented the data. The analysis presented here indicates that the hybrid embryo genotype is not fully expressed during both seed and seedling growth and development. The analysis presented here shows that seed growth and development are controlled by the sporophyte. The strong similarity in seed size and shape of the reciprocal hybrid seed with seeds of the maternal parents is evidence of this control. The analysis also indicates that since the maternal sporophyte controls seed size and therefore the amount of cotyledon reserves, the maternal sporophyte indirectly controls early seedling growth because the cotyledons are the primary nutrient source during heterotrophic growth. The most interesting and surprising results indicated that the maternal effects extended to the root architecture of the reciprocal hybrid seedlings. This phenomenon could not be explained by seed size, but by alterations in the control of the pattern of gene expression of the seedling, which apparently was set by a maternally controlled mechanism. Although seed weight increase was the main target of bean domestication, it also had positive repercussions on early-growth traits and stand establishment.

show abstract

“…ERF115 heterodimeric binding to different transcription factors induces downstream transcriptional reprograming, leading to dedifferentiation and proliferation ( 9 , 10 ). Activation of ERF115 expression has been linked in different contexts to multiple signals, including brassinosteroids, jasmonic acid, auxin, and reactive oxygen species ( 6 , 9 , 11 , 12 ). Although many of these upstream regulations have been implied, what defines the strict ERF115 spatial and temporal expression pattern remains elusive.…”

mentioning

confidence: 99%

Wounding-induced changes in cellular pressure and localized auxin signalling spatially coordinate restorative divisions in roots

Hoermayer

Montesinos

Marhavá

et al. 2020

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

Wound healing in plant tissues, consisting of rigid cell wall-encapsulated cells, represents a considerable challenge and occurs through largely unknown mechanisms distinct from those in animals. Owing to their inability to migrate, plant cells rely on targeted cell division and expansion to regenerate wounds. Strict coordination of these wound-induced responses is essential to ensure efficient, spatially restricted wound healing. Single-cell tracking by live imaging allowed us to gain mechanistic insight into the wound perception and coordination of wound responses after laser-based wounding inArabidopsisroot. We revealed a crucial contribution of the collapse of damaged cells in wound perception and detected an auxin increase specific to cells immediately adjacent to the wound. This localized auxin increase balances wound-induced cell expansion and restorative division rates in a dose-dependent manner, leading to tumorous overproliferation when the canonical TIR1 auxin signaling is disrupted. Auxin and wound-induced turgor pressure changes together also spatially define the activation of key components of regeneration, such as the transcription regulator ERF115. Our observations suggest that the wound signaling involves the sensing of collapse of damaged cells and a local auxin signaling activation to coordinate the downstream transcriptional responses in the immediate wound vicinity.

show abstract

Brassinazole resistant 1 (BZR1)-dependent brassinosteroid signalling pathway leads to ectopic activation of quiescent cell division and suppresses columella stem cell differentiation

Abstract: HighlightBrassinosteroids (BRs) lead to ectopic activation of quiescent centre division as well as modulation of the columella stem cells differentiation in Arabidopsis roots in a BR concentration- and BZR1-/BES1-dependent manner.

Cited by 54 publications

References 62 publications

Paracrine brassinosteroid signaling at the stem cell niche controls cellular regeneration

Paracrine brassinosteroid signaling at the stem cell niche controls cellular regeneration

Maternal Effects on Seed and Seedling Phenotypes in Reciprocal F1 Hybrids of the Common Bean (Phaseolus vulgaris L.)

Wounding-induced changes in cellular pressure and localized auxin signalling spatially coordinate restorative divisions in roots

Contact Info

Product

Resources

About