1989
DOI: 10.1111/j.1365-2133.1989.tb01332.x
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Brawny cutaneous induration and granulomatous panniculitis in large cell non-Hodgkin's (T suppressor/cytotoxic cell) lymphoma

Abstract: A 56-year-old lady presented with striking peau d'orange-like, woody, diffuse infiltration of the skin of the upper, inner aspects of both arms and thighs. Initial biopsy specimens showed a granulomatous panniculitis with non-specific lymphohistiocytic infiltration. Clinical deterioration occurred with development of ascites and peripheral oedema; a single axillary node became palpable. Cytology of ascitic fluid, and histology and immunopathology of the axillary node, and of a further skin biopsy, now revealed… Show more

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Cited by 29 publications
(14 citation statements)
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“…Prominent epithelioid cell response and/or epithelioid granuloma formation can rarely occur in association with other rare subtypes of CTCL (i.e. primary cutaneous CD4‐positive CTCL, subcutaneous T‐cell lymphomas) 46–48 …”
Section: Discussionmentioning
confidence: 99%
“…Prominent epithelioid cell response and/or epithelioid granuloma formation can rarely occur in association with other rare subtypes of CTCL (i.e. primary cutaneous CD4‐positive CTCL, subcutaneous T‐cell lymphomas) 46–48 …”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, a prominent epithelioid cell response and/or epithelioid granuloma formation T‐cell lymphoma has rarely been reported in other types of primary cutaneous lymphomas [ i.e. primary cutaneous CD30 negative small/medium and large T‐cell lymphoma (24, 28), subcutaneous T‐cell lymphomas (6, 25, 29), or primary cutaneous CD30 positive lymphoma (26)].…”
Section: Discussionmentioning
confidence: 99%
“…These lesions are manifested as papules, nodules, or a diffuse induration of the skin. Cutaneous granulomatous reactions have been observed to develop at any time during the evolution of the disease, and occasionally they can be a presenting sign of the disease (22, 25, 26).…”
Section: Discussionmentioning
confidence: 99%
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“…Außerdem zeigten sich Infiltrate atypischer Lymphozyten in den subkutanen Knoten und im Lymphknoten. Nur in wenigen Fällen ist ein Befall von Lymphknoten in der Literatur beschrieben [1,6,10,11,15,20].…”
Section: Diskussionunclassified