Brazilian-Portuguese Validation Assessment of the Gastrointestinal Quality of Life Index for Patients After Laparoendoscopic Cholecystectomy

Posegger, Karin Romano; Maeda, Carlos Toshinori; Taveira, Juliana Posegger; Caetano, E. M.; Ferraz, Marcos Bosi; Rocha, Maria José Azevedo de Brito; Filho, Gaspar de Jesus Lopes; Linhares, Marcelo Moura

doi:10.1089/lap.2020.0921

Cited by 7 publications

(5 citation statements)

References 23 publications

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“…The lower the GIQLI score, the worse the GI quality of life. Based on previous research, the cutoff for a low GIQLI score in this study was 126 points [13,14]. A total score of ≥ 126 was considered a high GIQLI score.…”

Section: Questionnairesmentioning

confidence: 99%

Identifying Gut Microbiota associated with Gastrointestinal Symptoms upon Roux-en-Y Gastric Bypass

et al. 2023

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Purpose Roux-en-Y gastric bypasses (RYGB) are frequently accompanied by long-term gastrointestinal (GI) symptoms. Direct mechanistic insight into the causation of these symptoms is lacking, but changes in the intestinal microbiome have been proposed to play a role. With this study, we aimed to investigate whether a microbial predisposition exists before RYGB which is associated with GI symptoms during follow-up and to evaluate which microbial groups are involved. Materials and Methods In total, 67 RYGB patients were included. Shotgun metagenomic sequencing was performed on fecal samples obtained just before and 1 year after surgery. To assess GI symptoms, patients filled out Gastrointestinal Quality of Life Index (GIQLI) questionnaires and were divided into groups based on their total GIQLI score and change in score (postsurgery versus baseline). Extremely randomized tree predictor models were used to identify the most distinctive microbial species associated with postoperative GI symptoms. Results Beta diversity differed significantly between baseline and 1-year post-surgery samples, with the post-surgery microbiome resembling a more dysbiotic profile. The most predictive species regarding total GIQLI (AUC 0.77) or delta GIQLI score (AUC 0.83) were identified. Many of these species are known butyrate producers or species known to support them and/or species with anti-inflammatory properties, including Coprococcus eutactus, Faecalibacterium prausnitzii, and Ruminococcus callidus. Conclusion Beneficial commensal gut microbiota related to a high GI score were associated to adequate intestinal fermentative capacity, suggesting these species might have protective properties against postoperative GI malfunctioning. Graphical Abstract

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Section: Questionnairesmentioning

confidence: 99%

Identifying Gut Microbiota associated with Gastrointestinal Symptoms upon Roux-en-Y Gastric Bypass

et al. 2023

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“…The GIQLI is an established instrument for clinical evaluation and research in gastrointestinal (GI) diseases and was established and first validated in German and subsequently in English language [ 5 , 10 ]. Currently, the GIQLI has been validated for several other languages [ 11 – 16 ]. The latter allows for a broad application of this instrument in research in different countries and cultures, which allows for interesting comparisons [ 10 – 16 ].…”

Section: Introductionmentioning

confidence: 99%

“…Currently, the GIQLI has been validated for several other languages [ 11 – 16 ]. The latter allows for a broad application of this instrument in research in different countries and cultures, which allows for interesting comparisons [ 10 – 16 ].…”

Section: Introductionmentioning

confidence: 99%

Quality of life in benign colorectal disease—a review of the assessment with the Gastrointestinal Quality of Life Index (GIQLI)

Fuchs,

Musial,

Retzbach

et al. 2023

Int J Colorectal Dis

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Background and purpose The Gastrointestinal Quality of Life Index (GIQLI) is an instrument for the assessment of quality of life (QOL) in diseases of the upper and lower GI tract, which is validated in several languages around the world. The purpose of this literature review is the assessment of the GIQLI in patients with benign colorectal diseases. Reports on GIQLI data are collected from several institutions, countries, and different cultures which allows for comparisons, which are lacking in literature. Methods The GIQL Index uses 36 items around 5 dimensions (gastrointestinal symptoms (19 items), emotional dimension (5 items), physical dimension (7 items), social dimension (4 items), and therapeutic influences (1 item). The literature search was performed on the GIQLI and colorectal disease, using reports in PubMed. Data are presented descriptively as GIQL Index points as well as a reduction from 100% maximum possible index points (max 144 index points = highest quality of life). Results The GIQLI was found in 122 reports concerning benign colorectal diseases, of which 27 were finally selected for detailed analysis. From these 27 studies, information on 5664 patients (4046 female versus 1178 male) was recorded and summarized. The median age was 52 years (range 29–74.7). The median GIQLI of all studies concerning benign colorectal disease was 88 index points (range 56.2–113). Benign colorectal disease causes a severe reduction in QOL for patients down to 61% of the maximum. Conclusions Benign colorectal diseases cause substantial reductions in the patient’s QOL, well documented by GIQLI, which allows a comparison QOL with other published cohorts.

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“…The Gastrointestinal Quality of Life Index (GIQLI) is a well-established instrument for the assessment of QOL in GI diseases and was established, validated, and published in German and English 25 years ago [7][8][9]. To date, this instrument has been validated for several other languages, which is an advantage because it makes research on QOL between different countries and cultures comparable, despite culture-specific aspects in respective countries [8,9,[16][17][18][19][20][21].…”

Section: Introductionmentioning

confidence: 99%

Gastrointestinal Quality of Life in Gastroesophageal Reflux Disease: A Systematic Review

2022

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Background: The Gastrointestinal Quality of Life Index (GIQLI) is a well-established instrument for the assessment of quality of life (QOL) in gastrointestinal (GI) diseases. The purpose of this literature review was to investigate QOL by means of GIQLI in patients with gastroesophageal reflux disease (GERD) prior to any interventional therapy. There are several reports on GIQLI data; however, comparisons from different countries and/or different GERD cohorts assessing the same disease have to date not been conducted. Methods: The GIQLI uses 36 items around 5 dimensions (GI symptoms [19 items], emotional dimension [5 items], physical dimension [7 items], social dimension [4 items], and therapeutic influences [1 item]). A literature search was conducted on the application of GIQLI in GERD patients prior to interventional therapy using reports in PubMed. Data on the mean GIQLI as well as index data for the 5 dimensions as originally validated were extracted from the published patient cohorts. A comparison with the normal healthy control group from the original publication of the GIQLI validation conducted by Eypasch was performed. Data are presented descriptively as GIQLI points as well as a reduction from 100% maximum possible index points (max 144 index points = highest QOL). Results: In total, 77 abstracts from studies using the GIQLI on patients with GERD were identified. After screening for content, 21 publications were considered for further analysis. Ten studies in GERD patients comprised complete calculations of all dimensions and were included in the analysis. Data from 1,682 study patients were evaluated with sample sizes ranging from 33 to 568 patients (median age of 789 females and 858 males: 51.8 years). The median overall GIQLI for the patient group was 91.7 (range 86–102.4), corresponding to 63.68% of the maximum GIQLI. The dimensions with the largest deviation from the respective maximum score were the physical dimension (55% of maximum) followed by the emotional dimension (60% of maximum). In summary, the GIQLI level in GERD cohorts was reduced to 55–75% of the maximum possible index. Conclusions: Severe GERD causes substantial reductions in the patient’s QOL. The level of GIQLI can carry between different studied GERD cohorts from different departments and countries. GIQLI can be used as an established tool to assess the patient’s condition in various dimensions.

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Brazilian-Portuguese Validation Assessment of the Gastrointestinal Quality of Life Index for Patients After Laparoendoscopic Cholecystectomy

Cited by 7 publications

References 23 publications

Identifying Gut Microbiota associated with Gastrointestinal Symptoms upon Roux-en-Y Gastric Bypass

Identifying Gut Microbiota associated with Gastrointestinal Symptoms upon Roux-en-Y Gastric Bypass

Quality of life in benign colorectal disease—a review of the assessment with the Gastrointestinal Quality of Life Index (GIQLI)

Gastrointestinal Quality of Life in Gastroesophageal Reflux Disease: A Systematic Review

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