Breast Cancer Cutaneous Metastasis at Core Needle Biopsy Site

Abstract

Cutaneous metastasis from breast cancer can occur by direct invasion, lymphatic and vascular spread as well as iatrogenic implantation. Metastasis that occurs by iatrogenic implantation after needle biopsy is very rare but the potential risk must be considered. In this report, we describe a case of breast cancer cutaneous metastasis that occurred by iatrogenic implantation following core needle biopsy. A 53-year-old woman presented with a 1×1 cm sized erythematous nodule at the biopsy site after breast conserving surgery for primary cancer. Histopathological findings confirmed cutaneous metastasis. The possibility of this consequence must be considered when performing needle biopsies.

Malignant Cytology in Washings of Mohs Micrographic Surgery Instruments

“…Many surgical specialties have reported implantation of malignant cells intraoperatively, leading to tumor recurrence or metastases . A study on glove and instrument washings after resection of head and neck squamous cell carcinomas demonstrated that 73% of washings had malignant cytology .…”

“…M any surgical specialties have reported implantation of malignant cells intraoperatively, leading to tumor recurrence or metastases. 1,2 A study on glove and instrument washings after resection of head and neck squamous cell carcinomas demonstrated that 73% of washings had malignant cytology. 3 Hussain and colleagues 4 recently reported a case of implantation of a squamous cell carcinoma at a donor graft site, thought to have arisen because of contamination of the hollow needle used to infiltrate local anaesthetic.…”

Multiple eruptive dermatofibromas occuring in a patient under hemodialysis

“…One additional mechanism for cutaneous metastasis not discussed in the Turkish study is iatrogenic implantation, such as that seen in the case presented by Cho et al in which a 53 year old female with invasive ductal carcinoma presented with a metastatic skin lesion 3yrs after ultrasound guided core needle biopsy at the site. Their investigation supported the recommendation for excision of the needle tract at the time of definitive surgery for invasive breast cancers [11].…”

Cancer Cell Seeding Following Manipulation: An Ancient Concern According to the Traditional Iranian Medicine

“…Several studies suggest that FNA can rarely cause needle track seeding or cutaneous metastasis at Biopsy Site in renal, pancreatic and hepatic (primary or metastatic) cancers [9][10][11]. As well, a few cases of breast cancer with the same complication after CNB have been reported [12,13]. There are also studies implying that procedures like prostate biopsy or surgical removal of the tumor during a colonoscopy (in colorectal cancer) may increase the number of circulating tumor cells (CTCs) in the blood in some cases [14,15].…”