Breast Cancer in Men: Characteristics Epidemiological, Clinicopathological and Therapeutic

Abstract

Background: Breast cancer is the leading malignancy in women, but it is relatively rare in men, accounting for 1% of all breast cancers. In Morocco, its incidence is 0.8/ 100,000 in men. This condition epidemiology, therapeutic and prognostic remains unknown given the scarcity of reported series. The objective of this work is to identify the epidemiological, clinical, pathological and therapeutic of this cancer in men. Results: Six patients were diagnosed with breast cancer with a ratio of 6/1277 cases. The mean age of patients was 63.3 ± 9.7 ans; the most common histological type was invasive ductal carcinoma (83.3%). The grade 2 SBR has a majority (66.7%), while that of SBR 3 is less represented (33.3%). A positive estrogen receptor (66.7% of cases) and progesterone (50.0% of cases) was noted. The HER2 receptor is overexpressed in 25% of cases. The treatment was essentially surgical (83.3%). Additional treatment included adjuvant chemotherapy (50.0%), radiotherapy (50.0%) and hormonal therapy (16.7%) was administered. Discussion/Conclusion: Breast cancer in men is rare and appears to have a very close clinical, histological characteristics and prognosis to those of elderly women. The diagnosis is usually late and tumors are treated in advanced stages. An improved prognosis requires better awareness for early detection.

Clinical Profile of Male Patients Presenting with Breast Cancer in Kashmir Valley

“…19 Most of the patients 4 (50%) in our study had grade 1 tumors unlike other studies reporting grade 2 tumors as the common. 20 Out of 8 patients 6 (75%) were in stage II and III (37.5%) each, while other studies report majority with stage II disease. 21 This variation may be attributed to small sample size and other geographical and ethnic factors and needs further study.…”

Frecuencia y características clinicopatológicas de mujeres obesas con cáncer de mama del Departamento de Oncología del Hospital de Clínicas

“…En este estudio se encontró una frecuencia mayor de cáncer de mama del subtipo histológico ductal infiltrante similar al estudio realizado por Maffuz-Aziz et al en México (23) y de Bueno realizado en Perú (24) . El subtipo histológico más frecuente de cáncer de mama en mujeres a nivel mundial es el ductal infiltrante (25,26) , en este estudio no difiere de los resultados de otros estudios.…”