Breast cancer screening—opportunistic use of registry and linked screening data for local evaluation

Roder, David; Farshid, Gelareh; Gill, Grantley; Kollias, Jim; Koczwara, Bogda; Karapetis, Christos S.; Adams, Jacqui; Joshi, Rohit; Keefe, Dorothy; Powell, Kate; Fusco, Kellie; Eckert, Marion; Buckley, Elizabeth; Beckmann, Kerri

doi:10.1111/jep.12640

Cited by 5 publications

(9 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Regular screening for breast cancer, as mentioned in the scientific literature, facilitates prompt detection of breast cancer and hence early intervention which potentially leads to lower mortality rates (11). Out of the 120 studied cases, one case was incidentally detected, six cases were detected by routine mammogram screening, and 97 cases were by self-exam.…”

Section: Discussionmentioning

confidence: 93%

Breast cancer epidemiology among surgically treated patients in Jordan: A retrospective study

Halbony

Salman

Alqassieh

et al. 2020

mjiri

View full text Add to dashboard Cite

Background: Multiple risk factors contribute to the development of breast cancer, including age, positive family history, early menarche, late menopause and the strongest factor being female gender. In this study, we aimed to investigate the proportion of breast cancer patients with certain risk factors, the prevalence of each cancer type, in addition to the surgical procedures performed.Methods: The medical records of patients diagnosed with breast cancer from January 2010 to November 2015 were evaluated retrospectively regarding demographics, breast cancer risk factors, comorbidities, diagnostic methods, tumor location, cancer type and stage, pathological findings, tumor markers, harvested lymph nodes and the types of surgical procedures. The collected data were statistically analyzed as number, mean, and frequency as percentages. Cases with deficient medical records were excluded from the analysis of certain parameters.Results: The sample consisted of 120 patients, 118 (98.3%) of whom were women. The mean age was 56.5±12.0 years. The most common diagnostic method at presentation was self-exam in 93.3% of patients. Invasive ductal carcinoma was the most common type of tumor (80.0%). The pathological stages could be determined for only 106 patients, and 26 patients (24.5%) were at stage 1 disease, 45 patients (42.5%) were at stage 2 whereas 34 patients (32.1%) were at stage 3. According to the results of pathological examinations, 72.6% (85 patients) of the cases were estrogen receptor positive, 61.2% (71 patients) were progesterone receptor positive while 24.8% (27 patients) were HER positive. Modified radical mastectomy (MRM) was performed in 52 (43.3%) patients and wide local excision (WLE) was preferred in 46 (38.3%) cases. Conclusion:Advanced age, positive family history, and prolonged estrogen exposure were remarkable in the majority of patients. Moreover, the most common type of breast cancer was invasive ductal carcinoma, and around half of the patients presented at stage 2 disease. Modified radical mastectomy and WLE were the most commonly performed surgical procedures.

show abstract

Section: Discussionmentioning

confidence: 93%

Breast cancer epidemiology among surgically treated patients in Jordan: A retrospective study

Halbony

Salman

Alqassieh

et al. 2020

mjiri

View full text Add to dashboard Cite

show abstract

“…Primary site was coded according to International Classification of Disease (Version 3) (ICD‐O‐3) criteria, or corresponding ICD‐9 codes for earlier years, and histology type using ICD‐O‐3 or Systemized Nomenclature of Medicine (SNOMED II) codes for earlier years . Tumour characteristics were extracted from pathology reports .…”

Section: Methodsmentioning

confidence: 99%

Female breast cancer management and survival: The experience of major public hospitals in South Australia over 3 decades—trends by age and in the elderly

Roder

Farshid

Kollias³

et al. 2017

Evaluation Clinical Practice

Self Cite

View full text Add to dashboard Cite

Breast-cancer survival increases applied to all ages, including 80+ years, but poorer outcomes persisted in this older group and the gap did not reduce. A key question is whether the best trade-off now exists between optimally therapeutic cancer treatment and accommodations for frailty and co-morbidity in the aged, or whether opportunities exist for better trade-offs and better survival. Local registry data are important for describing local service activity and outcomes by age for local service providers, health administrations and consumer groups; monitoring disparities; and indicating effects of local initiatives.

show abstract

“…Different rates of surgery have been reported by state and territory jurisdictions with Aboriginal and Torres Strait Islander women receiving comparable treatment to non-Indigenous women in Queensland [18] but significantly less surgical intervention in New South Wales (NSW) [19]. A national analysis of women participating in breast screening found, however, that Aboriginal and Torres Strait Islander women were more likely than other women to undergo mastectomy rather than breast conserving surgery [6, 16].…”

Section: Introductionmentioning

confidence: 99%

“…CanDAD has previously described the role of Aboriginality, cancer stage at diagnosis and broad treatment modalities in cancer outcomes for all cancer types collectively [3, 21]. Female breast screening service records [6, 16] were also available and facilitated an additional step in quantifying the clinical pathway for the subgroup of Aboriginal women diagnosed with breast cancer [22]. This will assist with developing an improved national understanding of breast cancer outcomes.…”

Section: Introductionmentioning

confidence: 99%

Disparities in breast screening, stage at diagnosis, cancer treatment and the subsequent risk of cancer death: a retrospective, matched cohort of aboriginal and non-aboriginal women with breast cancer

Banham

Roder

Keefe

et al. 2019

BMC Health Serv Res

Self Cite

View full text Add to dashboard Cite

Background Australia’s Aboriginal and Torres Strait Islander women have poorer survival and twice the disease burden from breast cancer compared to other Australian women. These disparities are influenced, but not fully explained, by more diagnoses at later stages. Incorporating breast screening, hospital and out of hospital treatment and cancer registry records into a person-linked data system can improve our understanding of breast cancer outcomes. We focussed one such system on a population-based cohort of Aboriginal women in South Australia diagnosed with breast cancer and a matched cohort of non-Aboriginal women with breast cancer. We quantify Aboriginal and non-Aboriginal women’s contact with publicly funded screening mammograms; quantify exposure to a selection of cancer treatment modalities; then assess the relationship between screening, treatment and the subsequent risk of breast cancer death. Methods Breast cancers registered among Aboriginal women in South Australia in 1990–2010 ( N = 77) were matched with a random selection of non-Aboriginal women by birth and diagnostic year, then linked to screening records, and treatment 2 months before and 13 months after diagnosis. Competing risk regression summarised associations of Aboriginality, breast screening, cancer stage and treatment with risk of breast cancer death. Results Aboriginal women were less likely to have breast screening (OR = 0.37, 95%CIs 0.19–0.73); systemic therapies (OR = 0.49, 95%CIs 0.24–0.97); and, surgical intervention (OR = 0.35, 95%CIs 0.15–0.83). Where surgery occurred, mastectomy was more common among Aboriginal women (OR = 2.58, 1.22–5.46). Each of these factors influenced the risk of cancer death, reported as sub-hazard ratios (SHR). Regional spread disease (SHR = 34.23 95%CIs 6.76–13.40) and distant spread (SHR = 49.67 95%CIs 6.79–363.51) carried more risk than localised disease (Reference SHR = 1). Breast screening reduced the risk (SHR = 0.07 95%CIs 0.01–0.83). So too did receipt of systemic therapy (SHR = 0.06 95%CIs 0.01–0.41) and surgical treatments (SHR = 0.17 95%CIs 0.04–0.74). In the presence of adjustment for these factors, Aboriginality did not further explain the risk of breast cancer death. Conclusion Under-exposure to screening and treatment of Aboriginal women with breast cancers in South Australia contributed to excess cancer deaths. Improved access, utilisation and quality of effective treatments is needed to improve survival after breast cancer diagnosis.

show abstract

Breast cancer screening—opportunistic use of registry and linked screening data for local evaluation

Cited by 5 publications

References 29 publications

Breast cancer epidemiology among surgically treated patients in Jordan: A retrospective study

Breast cancer epidemiology among surgically treated patients in Jordan: A retrospective study

Female breast cancer management and survival: The experience of major public hospitals in South Australia over 3 decades—trends by age and in the elderly

Disparities in breast screening, stage at diagnosis, cancer treatment and the subsequent risk of cancer death: a retrospective, matched cohort of aboriginal and non-aboriginal women with breast cancer

Contact Info

Product

Resources

About