Breast-conserving surgery and sentinel lymph node biopsy for breast cancer and their correlation with the expression of polyligand proteoglycan-1

Li, Fuming; Xu, Dan-Ying; Xu, Qi

doi:10.12998/wjcc.v10.i10.3113

Cited by 2 publications

(1 citation statement)

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“…Although both breast conserving surgery and mastectomy are relatively low morbidity procedures and have low early postoperative complications, breast conserving surgery has fewer postoperative complications. 21,22 In our study, quadrantectomy was done in 7 patients while 4 had wide local excision. A quadrantectomy is designed to remove an anatomic segment of breast tissue (ductlobular system).…”

Section: Discussionmentioning

confidence: 95%

Initial experience with breast conserving surgery in Jos

et al. 2023

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Background: Breast conserving surgery is the treatment of choice in the surgical management of early-stage breast cancer in developed countries, while mastectomy has remained the most practiced surgical treatment in developing countries. The aim of the study was to describe the outcomes of a cohort of patients who had breast conserving surgery in a developing country. Methods: The study is a retrospective review of patients who were offered breast conserving surgery between January 2018 and December 2020 at the Jos University Teaching Hospital and FOMAS Hospital. Results: A total of 110 female patients had surgery for breast cancer in the study period. Of this number, eleven (10%) patients whose ages ranged from 28-70 years with a mean age of 53.5 years (SD=12.9 years) had breast conserving surgery, while 99 (90%) had mastectomy. A painless lump on self-breast examination was the most common reason for presentation in those who had breast conserving surgery. Most of the patients who had breast conserving surgery presented with tumor stage T2N1M0. Quadrantectomy was done in 7 (63.6%) patients while 4 (36.4%) had wide local excision. No patient developed any postoperative complication. No patient required re-excision due to positive margins. Three (27.3%) patients had only adjuvant hormonal therapy. Eight (72.7%) patients had radiotherapy following surgery, while 3 (27.3%) patients had only breast conserving surgery for loco-regional control. All patients had a minimum follow up of 2 years with no recurrence or mortality. Conclusions: Breast conserving surgery can be safely practiced as an alternative to mastectomy in carefully selected patients with early breast cancer with good outcomes.

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Section: Discussionmentioning

confidence: 95%