Breast fibromatosis associated with breast implants

Abstract

Fibromatosis refers to an extra-abdominal desmoid tumor or aggressive fibromatosis. Breast fibromatosis can develop in association with the capsule around a breast implant, although reports of cases of fibromatosis associated with breast implants are rare. As the demand for breast augmentation has increased, it is important to understand the diseases associated with breast implants. In the present report, we describe a case of breast fibromatosis that developed adjacent to a breast implant and demonstrated a relatively well-defined border even though it invaded the surrounding structures. We also explore the specific imaging features for diagnosing breast fibromatosis in association with implants by reviewing previous literature.

Radiologic images of an aggressive implant-associated fibromatosis of the breast and chest wall: case report and review of the literature

“…Immunohistochemical stains revealed the spindle cells were positive for vimentin, beta-catenin, and with foci of positivity for smooth muscle actin. The lesion had predominantly negative results for CD34, CD54, S100, estrogen receptor antibody, 903, and pan-cytokeratin; the findings further supported the diagnosis of fibromatosis [10] , [11] , [12] , [13] . A week following the core biopsy, a contrast-enhanced computed tomography (CT) of the chest was performed demonstrating a hypoattenuating circumscribed mass in the left breast compatible with known fibromatosis causing anterolateral displacement of the breast implant ( Figs 2 A and B ).…”

Bilateral desmoid tumor of the breast: case series and literature review

“…Most of them occur sporadically;5 however, intra-abdominal desmoid tumors seem to be related to FAP or GS and any germ line mutation 13. A prior history of trauma has been reported to be associated with this tumor in one of every four patients14 and has also been associated with fibromatosis of the breast and breast augmentation 2,5,12,15,16. Fibromatosis of the breast can occur primarily due to breast parenchyma and by secondary invasion from the musculoaponeurotic layer of the pectoral muscle.…”

Papillary endothelial hyperplasia (Masson's tumor) developed in the capsule of the implant in a breast cancer patient treated with mastectomy and radiation therapy

“…Fibromatosis (desmoid tumor) is a rare entity arising from breast parenchyma, the musculo‐aponeurotic layer of the pectoralis muscle, or rarely the capsule around a breast implant . The appearance is usually a circumscribed mass, but infiltrative margins may also be apparent.…”

“…11 Fibromatosis (desmoid tumor) is a rare entity arising from breast parenchyma, the musculo-aponeurotic layer of the pectoralis muscle, or rarely the capsule around a breast implant. 12 The appearance is usually a circumscribed mass, but infiltrative margins may also be apparent. On MRI, a mass lesion most frequently iso-intense to muscle on T1-weighted sequences and of variable high-signal intensity on T2-weighted sequences is seen sometimes with a typical hypointense band.…”