Breast Implant–Associated Anaplastic Large Cell Lymphoma

Abstract

Breast implant-associated anaplastic large cell lymphoma is a rare cancer in patients with breast implants but is increasing in incidence. It is important for all physicians involved in the care of patients with breast implants to be aware of this entity and be able to recognize initial symptoms.

Granulomatous slack skin mycosis fungoides developing simultaneously with sarcoid‐like lesions in a patient with repeated anabolic injections in the past?

“…On the one hand, probable infectious or non-infectious antigens could be exogenously incorporated (such as exogenous pigment of a tattoo), and on the other hand de novo tumor antigens could arise within the framework of a malignant process (Tchernev et al, 2014;Tchernev et al, 2018;Tchernev & Wollina, 2013). (h) Elastin staining shows a marked decrease in elastic tissue in the right axillary area particular interest (Fitzal, Turner, & Kenner, 2019;Leberfinger et al, 2017). Reactive lymphadenopathy, not typical for sarcoidosis of the lymph node; 40, HE staining.…”

“…By definition, it is believed that as a result of MM, a valid cross-activation of human B and/or T cells is generated, and in this respect, the cases of breast implant-associated anaplastic large cell lymphomas are of Within the lymph node is a collection of epitheloid cells/macrophages. In these cases, the probability is that chronic infections and/or implant toxins are likely to result in malignant transformation of T cells that are anaplastic lymphoma kinase (ALK) negative and CD30 positive (Fitzal et al, 2019;Leberfinger et al, 2017). (f-h) Microscopic findings in the skin from the right axillary region.…”

“…(h) Elastin staining shows a marked decrease in elastic tissue in the right axillary area particular interest (Fitzal, Turner, & Kenner, 2019;Leberfinger et al, 2017). In these cases, the probability is that chronic infections and/or implant toxins are likely to result in malignant transformation of T cells that are anaplastic lymphoma kinase (ALK) negative and CD30 positive (Fitzal et al, 2019;Leberfinger et al, 2017). The mechanisms by which these lymphomas are generated are not fully elucidated, but the role of molecular mimicry should not be neglected.…”

Cytological features of breast implant‐associated anaplastic large cell lymphoma in pleural effusion

“…Cosmetic surgery patients frequently do not follow-up with their plastic surgeon in postoperative years. 25 Abbreviation: NR, not reported.…”

“…The cytoplasm was abundant and delicate. 25 [17][18][19] The results of our literature search are summarized in Table 1.…”