Breast Implants and Breast Cancer Screening

Smalley, Stacy M

doi:10.1016/s1526-9523(03)00280-0

Cited by 19 publications

(11 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Breast implants pose a particular problem when evaluating female patients for the presence of heart disease or breast cancer [10,13]. They can be a significant source of radiotracer attenuation during myocardial SPECT imaging, and they can also make imaging of the heart by other means such as echocardiography more difficult.…”

Section: Discussionmentioning

confidence: 99%

Impaired myocardial SPECT imaging secondary to silicon- and saline-containing breast implants

Stinis

Lizotte

Movahed

2006

Int J Cardiovasc Imaging

View full text Add to dashboard Cite

Early detection of coronary artery disease (CAD) in women has been challenging. Women are more likely to present with atypical symptoms, and non-invasive evaluation for CAD has been less accurate. Myocardial SPECT imaging is a well-established technique that provides important physiologic, anatomic, and prognostic information in women. Attenuation artifacts secondary to breast tissue are a common problem in women and can lead to decreased specificity of gated SPECT imaging. Cosmetic breast implants are increasing in popularity. The presence of a foreign object overlying the anterior wall of the heart in addition to native breast tissue can significantly increase attenuation artifacts. There is only one report to date describing attenuation artifact due to silicon breast implants in comparison to control, and there are no reports regarding saline breast implants. Here we report three cases of impaired myocardial SPECT imaging in women with breast implants: one patient with silicone implants, and two with saline-containing implants. Clinicians should be aware of this problem and women should be educated regarding the potential future diagnostic problems that may occur with breast implants before considering this cosmetic surgery.

show abstract

Section: Discussionmentioning

confidence: 99%

Impaired myocardial SPECT imaging secondary to silicon- and saline-containing breast implants

Stinis

Lizotte

Movahed

2006

Int J Cardiovasc Imaging

View full text Add to dashboard Cite

show abstract

“…65 The amount of parenchymal breast tissue obscured at mammography by the implant is known to be between 22% and 83%. 66 Insufficient compression of the breast to visualize the parenchyma and the production of implant related artifacts on the film can also make interpretation of mammographic examinations difficult in women with augmented breasts. 28 29 Additionally, capsular contracture, which develops in about 15-20% of women with implants, has been shown to reduce mammographic sensitivity by 30-50%.…”

Section: Possible Explanations For Findingsmentioning

confidence: 99%

“…8 10 17 20 The breast implants could serve as a base against which the mass may be more likely to be differentiated. 73 This suggests that tumors of equal size may be more easily palpated in patients with implants, especially for implants placed in the subglandular position, 66 and this may compensate somewhat for the potential impairment of mammography. However, very few studies have evaluated this question, providing no conclusive results.…”

Section: Possible Explanations For Findingsmentioning

confidence: 99%

Breast cancer detection and survival among women with cosmetic breast implants: systematic review and meta-analysis of observational studies

Lavigne

Holowaty

Pan

et al. 2013

BMJ

View full text Add to dashboard Cite

Objectives To evaluate whether the stage distribution among women diagnosed as having breast cancer differs between those who have received breast implants for cosmetic purposes and those with no implants and to evaluate whether cosmetic breast augmentation before the detection of breast cancer is a predictor of post-diagnosis survival.Design Systematic review of observational studies with two meta-analyses.Data sources Systematic search of the literature published before September 2012 conducted in Medline, Embase, Global health, CINAHL, IPAB, and PsycINFO.Study selection Eligible publications were those that included women diagnosed as having breast cancer and who had had augmentation mammaplasty for cosmetic purposes. ResultsThe overall odds ratio of the first meta-analysis based on 12 studies was 1.26 (95% confidence interval 0.99 to 1.60; P=0.058; I 2 =35.6%) for a non-localized stage of breast cancer at diagnosis comparing women with implants who had breast cancer and women without implants who had breast cancer. The second meta-analysis, based on five studies, evaluated the relation between cosmetic breast implantation and survival. This meta-analysis showed reduced survival after breast cancer among women who had implants compared with those who did not (overall hazard ratio for breast cancer specific mortality 1.38, 95% confidence interval 1.08 to 1.75). ConclusionsThe research published to date suggests that cosmetic breast augmentation adversely affects the survival of women who are subsequently diagnosed as having breast cancer. These findings should be interpreted with caution, as some studies included in the meta-analysis on survival did not adjust for potential confounders. Further investigations are warranted regarding diagnosis and prognosis of breast cancer among women with breast implants.

show abstract

“…One possible explanation is that subglandular implants, because of their proximity with breast tissue, could serve as a base against which the mass may be easier to feel at breast examination and be more palpable compared with women with submuscular implant placement (33,58). This may compensate for the potential impairment in visualization (59,60). However, this explanation needs to be further confirmed (29,30,34).…”

Section: Principal Findings and Comparison With Previous Studiesmentioning

confidence: 99%

Do Breast Implants Adversely Affect Prognosis among Those Subsequently Diagnosed with Breast Cancer? Findings from an Extended Follow-Up of a Canadian Cohort

Lavigne

Holowaty

Pan

et al. 2012

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

Background: Cosmetic breast implants may impair the ability to detect breast cancers. The aims of this study were to examine whether implants and implant characteristics are associated with more advanced breast tumors at diagnosis and poorer survival.Methods: Study population includes all invasive breast cancer cases diagnosed during follow-up of the large Canadian Breast Implant Cohort. A total of 409 women with cosmetic breast implants and 444 women with other cosmetic surgery were diagnosed with breast cancer. These women were compared for stage at diagnosis using multinomial logistic regression models. Cox proportional hazards regression models were used for breast cancer-specific mortality analyses. Comparisons were also conducted according to implant characteristics.Results: Compared with women with other cosmetic surgery, those with cosmetic breast implants had at later stage breast cancer diagnosis (OR of having stage III/IV vs. stage I at diagnosis: 3.04, 95% confidence interval (CI): 1.81-5.10; P < 0.001). A nonstatistically significant increase in breast cancer-specific mortality rate for women with breast implants relative to surgical controls was observed (HR ¼ 1.32, 95% CI: 0.94-1.83, P ¼ 0.11). No statistically significant differences in stage and breast cancer mortality were observed according to implant characteristics.Conclusions: At diagnosis, breast cancers tended to be at more advanced stages among women with cosmetic breast implants. Breast cancer-specific survival was lower in these women although the reduction did not reach statistical significance.Impact: Further investigations of the effect of breast implants on breast cancer prognosis are warranted. Cancer Epidemiol Biomarkers Prev; 21(10); 1868-76. Ó2012 AACR.

show abstract

Breast Implants and Breast Cancer Screening

Cited by 19 publications

References 51 publications

Impaired myocardial SPECT imaging secondary to silicon- and saline-containing breast implants

Impaired myocardial SPECT imaging secondary to silicon- and saline-containing breast implants

Breast cancer detection and survival among women with cosmetic breast implants: systematic review and meta-analysis of observational studies

Do Breast Implants Adversely Affect Prognosis among Those Subsequently Diagnosed with Breast Cancer? Findings from an Extended Follow-Up of a Canadian Cohort

Contact Info

Product

Resources

About