2018
DOI: 10.1111/ppe.12478
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Breast milk transmission of flaviviruses in the context of Zika virus: A systematic review

Abstract: Because the health advantages of breast feeding are considered greater than the potential risk of transmission, the World Health Organization recommends that mothers with possible or confirmed Zika virus infection or exposure continue to breast feed. This review did not identify any data that might alter this recommendation.

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Cited by 55 publications
(56 citation statements)
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“…More evidence is needed to distinguish breastfeeding transmission from other perinatal transmission routes'. This is in line with the conclusion of a recent systematic review by Mann et al [26].…”
Section: Limited Evidencesupporting
confidence: 93%
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“…More evidence is needed to distinguish breastfeeding transmission from other perinatal transmission routes'. This is in line with the conclusion of a recent systematic review by Mann et al [26].…”
Section: Limited Evidencesupporting
confidence: 93%
“…This is in line with the conclusion of a recent systematic review by Mann et al . . Also, there is very limited evidence for perinatal transmission, which has been further investigated in a recent systematic review by Soriano‐Arandes . Transmission via blood products is a potential way of transmission, but the evidence is scarce. Most studies dealing with this way of transmission recommend testing for ZIKV in affected areas.…”
Section: Discussionmentioning
confidence: 99%
“…The current paradigm is that dengue is passed from human to human by the bite of an infected mosquito. However, reports of nonvector transmission are steadily escalated . Most of these nonvector DENV infections are underreported even in endemic countries.…”
Section: Discussionmentioning
confidence: 99%
“…Traditionally, DENV is transmitted to humans via the bite of the infectious female mosquitos of the genus Aedes , mainly A. aegypti . Recently, nonvector DENV transmission has been reported in the literature, including intravenous and/or intradermal inoculation, mucocutaneous exposure, blood transfusion, hematopoietic stem cell transplantation (HSCT), solid organ transplantation, needlestick in patient care or laboratory accident, vertical transmission from mother to infant, and breastfeeding . This line of evidence suggests that DENV can be transmitted through direct exposure through blood/body fluid exposure, leading to disease.…”
mentioning
confidence: 99%
“…Other body fluid transmissions: current evidence shows that ZIKV RNA has been isolated in blood, amniotic fluid, semen, urine, saliva, breast milk [5,64], and cerebrospinal fluid, indicating the significant potential of fluid transmission [2,5,65]. ZIKV in saliva has been documented to be twice as much as that in blood, implying the enormous possibility of ZIKV transmission.…”
Section: Non-vector Borne Transmissionsmentioning
confidence: 99%