Breast MR Imaging: Current Indications and Advanced Imaging Techniques

Weinstein, Susan P.; Rosen, Mark

doi:10.1016/j.rcl.2010.06.011

Cited by 58 publications

(43 citation statements)

References 156 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In malignant tumors, the new blood vessels have increased permeability resulting in rapid high enhancement after contrast injection followed by rapid contrast washout. This enhancement pattern leads to type 3 TIC (Weinstein and Rosen, 2010). The pairwise comparison of the ROC curves for each of these functional MR techniques showed that TIC type is a more accurate technique comparing to DWI and ADC value, for distinguishing benign from malignant adnexal masses.…”

Section: 3407 Differentiation Of Benign From Malignant Adnexal Massementioning

confidence: 95%

Differentiation of Benign from Malignant Adnexal Masses by Functional 3 Tesla MRI Techniques: Diffusion-Weighted Imaging and Time-Intensity Curves of Dynamic Contrast-Enhanced MRI

Malek

Pourashraf²,

Mousavi³

et al. 2015

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Section: 3407 Differentiation Of Benign From Malignant Adnexal Massementioning

confidence: 95%

Differentiation of Benign from Malignant Adnexal Masses by Functional 3 Tesla MRI Techniques: Diffusion-Weighted Imaging and Time-Intensity Curves of Dynamic Contrast-Enhanced MRI

Malek

Pourashraf²,

Mousavi³

et al. 2015

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

“…MRI is the best technique to assess tumor volume, including the invasion of the pectoral muscle in posterior tumors (18), with abnormal enhancement of the muscle in postgadolinium images (Fig. 1).…”

Section: Extension Inside the Breastmentioning

confidence: 99%

“…Therefore, it is necessary to confirm the diagnosis by percutaneous core biopsy after a second look focused on the MRI findings or to perform an MRI-guided biopsy, which is available in a few institutions, if additional foci are not observed by mammogram or US. Diffusion-weighted imaging (DWI), a noncontrast sequence of MRI, improves breast lesion characterization without decreasing the sensitivity, reducing the number of negative biopsies if multicentricity is suspected (18). Currently, routine pretreatment MRI in all patients with invasive ductal carcinoma remains controversial (4,8,13,18,(20)(21)(22)(23), but seems to be indicated in those patients with invasive lobular carcinoma.…”

Section: Extension Inside the Breastmentioning

confidence: 99%

“…Diffusion-weighted imaging (DWI), a noncontrast sequence of MRI, improves breast lesion characterization without decreasing the sensitivity, reducing the number of negative biopsies if multicentricity is suspected (18). Currently, routine pretreatment MRI in all patients with invasive ductal carcinoma remains controversial (4,8,13,18,(20)(21)(22)(23), but seems to be indicated in those patients with invasive lobular carcinoma. This condition has a higher risk of microscopic spread than invasive ductal carcinoma, allowing better-delimited tumor margins than mammography and US.…”

Section: Extension Inside the Breastmentioning

confidence: 99%

“…Large prospective randomized clinical trials are necessary to determine whether preoperative MRI can improve DFS or OS in patients with invasive lobular carcinoma (24). MRI is also indicated before neoadjuvant therapy in patients with potentially operable stage IIIa breast cancer (18,23) or at stage II if the tumor is too large with respect to the breast volume, provided that performing an MRI does not significantly postpone neoadjuvant therapy initiation (23). Pretreatment MRI facilitates comparison with postneoadjuvant therapy imaging, enabling accurate preoperative planning.…”

Section: Extension Inside the Breastmentioning

confidence: 99%

See 2 more Smart Citations

The current role of radiologists in a multidisciplinary team treating breast cancer

Cortázar-García

Portero²,

Acebal-Blanco³

et al. 2013

Diagn Interv Radiol

View full text Add to dashboard Cite

In the last decade, advances in the diagnosis and treatment of breast cancer have achieved a significant increase in the general and disease-free survival of affected women but have also increased the complexity of therapeutic decisions. The decision-making process requires agreement between the physicians involved in the management of these patients.Radiologists must understand what other physicians expect and inform them about the usefulness of imaging modalities. This review attempts to provide an update on these subjects.

show abstract

Imaging of Her2‐targeted magnetic nanoparticles for breast cancer detection: comparison of SQUID‐detected magnetic relaxometry and MRI

Adolphi

Butler

Lovato

et al. 2012

Contrast Media & Molecular

View full text Add to dashboard Cite

Both magnetic relaxometry and magnetic resonance imaging (MRI) can be used to detect and locate targeted magnetic nanoparticles, non-invasively and without ionizing radiation. Magnetic relaxometry offers advantages in terms of its specificity (only nanoparticles are detected) and the linear dependence of the relaxometry signal on the number of nanoparticles present. In this study, detection of single-core iron oxide nanoparticles by Superconducting Quantum Interference Device (SQUID)-detected magnetic relaxometry and standard 4.7 T MRI are compared. The nanoparticles were conjugated to a Her2 monoclonal antibody and targeted to Her2-expressing MCF7/Her2-18 breast cancer cells); binding of the nanoparticles to the cells was assessed by magnetic relaxometry and iron assay. The same nanoparticle-labeled cells, serially diluted, were used to assess the detection limits and MR relaxivities. The detection limit of magnetic relaxometry was 125,000 nanoparticle-labeled cells at 3 cm from the SQUID sensors. T2-weighted MRI yielded a detection limit of 15,600 cells in a 150 μl volume, with r1 = 1.1 mM−1s−1 and r2 = 166 mM−1s−1. Her2-targeted nanoparticles were directly injected into xenograft MCF7/Her2-18 tumors in nude mice, and magnetic relaxometry imaging and 4.7 T MRI were performed, enabling direct comparison of the two techniques. Co-registration of relaxometry images and MRI of mice resulted in good agreement. A method for obtaining accurate quantification of microgram quantities of iron in the tumors and liver by relaxometry was also demonstrated. These results demonstrate the potential of SQUID-detected magnetic relaxometry imaging for the specific detection of breast cancer and the monitoring of magnetic nanoparticle-based therapies.

show abstract

Breast MR Imaging: Current Indications and Advanced Imaging Techniques

Cited by 58 publications

References 156 publications

Differentiation of Benign from Malignant Adnexal Masses by Functional 3 Tesla MRI Techniques: Diffusion-Weighted Imaging and Time-Intensity Curves of Dynamic Contrast-Enhanced MRI

Differentiation of Benign from Malignant Adnexal Masses by Functional 3 Tesla MRI Techniques: Diffusion-Weighted Imaging and Time-Intensity Curves of Dynamic Contrast-Enhanced MRI

The current role of radiologists in a multidisciplinary team treating breast cancer

Imaging of Her2‐targeted magnetic nanoparticles for breast cancer detection: comparison of SQUID‐detected magnetic relaxometry and MRI

Contact Info

Product

Resources

About