Breast MRI in Pregnancy-Associated Breast Cancer

Abstract

The purpose of this study was to evaluate the usefulness of MR imaging and to describe the MR imaging findings of pregnancy-associated breast cancer. Materials and Methods: From 2006 to 2013, MR images of 23 patients with pregnancy-associated breast cancer were retrospectively evaluated. MR images were reviewed to evaluate lesion detection and imaging findings of pregnancy-associated breast cancer. MR images were analyzed by using the Breast Imaging Reporting and Data System and an additional MR-detected lesion with no mammographic or sonographic abnormality was determined. Results: MR imaging depicted breast cancer in all patients, even in marked background parenchymal enhancement. Pregnancy-associated breast cancer was seen as a mass in 20 patients and as non-mass enhancement with segmental distribution in 3 patients. The most common features of the masses were irregular shape (85%), non-circumscribed margin (85%), and heterogeneous enhancement (60%). An additional site of cancer was detected with MR imaging in 5 patients (21.7%) and the type of surgery was changed. Conclusion: Pregnancy-associated breast cancer was usually seen as an irregular mass with heterogeneous enhancement on MR images. Although these findings were not specific, MR imaging was useful in evaluating the disease extent of pregnancy-associated breast cancer. Index terms

Rebinding dynamics of NO to microperoxidase-8 probed by time-resolved vibrational spectroscopy

“…This range is consistent with the reported population of the vibrationally excited ligand after the photolysis of ligated Mb, a similar heme system. When MbNO and MbCO were photoexcited by a 575 nm photon, approximately 15% of NO 67 and 6% of CO, 77,78 respectively, were deligated in the vibrationally excited state. When the same energy is deposited into the deligated ligand, as more energy is partitioned into its vibrational energy, less energy will be partitioned into its translational energy, resulting in a smaller initial separation.…”

Breast lesions during pregnancy and lactation: a pictorial essay

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