Breast Tuberculosis

Thimmappa, Durganna; Mallikarjuna, M; Vijayakumar, Abhishek

doi:10.1007/s12262-015-1272-1

Cited by 39 publications

(113 citation statements)

References 45 publications

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“…The majority were well‐established migrants with a median of 9 years since entry to the UK, mirroring figures for migrants with TB nationally . Our cohort was predominantly young and female, in keeping with prior studies where a 1:30 male to female ratio has been estimated for breast TB . Nearly a quarter of the women in our cohort were pregnant or breastfeeding.…”

Section: Resultsmentioning

confidence: 99%

“…Nearly a quarter of the women in our cohort were pregnant or breastfeeding. Both are recognized risk factors for breast TB, perhaps attributable to increased breast vascularity, tissue damage, and mammary duct dilatation . Our low rates of HIV co‐infection reflect the national TB/HIV co‐infection rate of 2.8%…”

Section: Resultsmentioning

confidence: 99%

“…The main differential diagnosis of breast TB is breast cancer, and these entities can be difficult to distinguish radiologically . Ultrasound may be useful in enabling differentiation of solid from cystic lesions and in assessing axillary lymph nodes .…”

Section: Resultsmentioning

confidence: 99%

“…The presenting features may mimic other breast pathology including bacterial abscess, idiopathic granulomatous mastitis, or carcinoma making diagnosis challenging. Risk factors for the development of breast TB include immunosuppression, lactation, multiparity, and previous exposure to TB …”

Section: Introductionmentioning

confidence: 99%

“…The majority of previous breast TB series are reported from countries of high TB incidence, and there is limited evidence to aid clinical decision making in a low TB incidence country such as the UK . There are no national UK guidelines for the investigation and management of breast TB.…”

Section: Introductionmentioning

confidence: 99%

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Breast tuberculosis in East London: A 13‐year retrospective observational study

et al. 2019

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Setting Breast tuberculosis (TB) is rare in Western Europe, and its diagnosis may be delayed through lack of awareness of presenting features. Our institution serves a large East London population with a high incidence of TB. Objective To characterize presenting features and avoidable diagnostic delay in breast TB patients. Design We conducted a 13‐year retrospective study of breast TB patients treated at our institution including demographic, clinical, microbiology, and pathology data. Results Forty‐seven cases were included; 44 (94%) were female, with a median age of 33 years (IQR 28.5‐39.5). The main presenting feature was a breast lump in 41 cases (87%); which were predominantly solitary unilateral lesions (25, 61%) and frequently located in the upper outer quadrant (28, 68%). Where performed, Mycobacterium tuberculosis was cultured in 15/36 (42%) cases. Granulomata were present on biopsy or aspirate in 21 (47%) and 17 (36%) cases, respectively. The median duration between symptom onset and treatment was 20 weeks (IQR 15‐30). Forty‐six (98%) completed treatment successfully and one relapsed. Conclusion A high index of suspicion for TB is required for individuals presenting with breast symptoms from countries where TB is endemic. Development of standardized pathways may improve detection and management of breast TB may reduce diagnostic delay.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Breast tuberculosis in East London: A 13‐year retrospective observational study

et al. 2019

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An unusual presentation of breast tuberculosis: A case report

Rizzo

Colli

Marco

et al. 2020

Clinical Case Reports

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Bilateral breast tuberculosis: A case report

Molla,

Iberahim,

Alemu

et al. 2024

Clinical Case Reports

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Key Clinical MessageBreast tuberculosis is a rare clinical condition that has the potential to imitate breast cancer or pyogenic abscess. It is crucial to consider this in patients who have resistant breast abscesses or persistent sinuses, particularly in high‐risk groups or locations. The main treatment for breast tuberculosis is antitubercular treatment.AbstractBilateral breast tuberculosis is a rare form of the disease that affects breasts. It is most commonly seen in young females, including nulliparous and lactating women. Diagnosis of bilateral breast tuberculosis can be challenging due to its similarity to other breast diseases, such as granulomatous mastitis and breast carcinoma. Patients from high‐risk groups and/or endemic locations who present with clinically suspicious breast lumps or refractory breast abscesses should have breast TB taken into consideration in their differential diagnosis. A 24‐year‐old Ethiopian female presented to the surgical outpatient department with a complaint of bilateral breast pain of 1‐year duration associated with a low‐grade fever, not associated with chills or rigor. She also has ulceration on the lower part of both breasts. It was followed by pus discharge from the right breast 6 months later. Investigations, including fine needle aspiration cytology, were suggestive of tuberculous mastitis. Later, the patient was treated with antituberculous drugs for 6 months, and the above symptoms subsided. Individuals with breast lesions who do not respond well to antibiotics should be suspected of having breast tuberculosis, especially if they are young and reside in or were born in a nation where the disease is prevalent.

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Breast Tuberculosis

Abstract: Tuberculosis affects over a billion people w o r l d w i d e .

Cited by 39 publications

References 45 publications

Breast tuberculosis in East London: A 13‐year retrospective observational study

Breast tuberculosis in East London: A 13‐year retrospective observational study

An unusual presentation of breast tuberculosis: A case report

Bilateral breast tuberculosis: A case report

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