Breath-hold training of humans reduces oxidative stress and blood acidosis after static and dynamic apnea

Joulia, Fabrice; Steinberg, Johannes; Faucher, Marion; Jamin, Thibault; Ulmer, Christophe; Kipson, Nathalie; Jammes, Yves

doi:10.1016/s1569-9048(03)00110-1

Cited by 69 publications

(61 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the little changes in the antioxidant enzyme activities in erythrocytes and lymphocytes, together with the lack of oxidative damage in erythrocytes after diving reflect a production of ROS, which is balanced with their deactivation. Our modest changes in antioxidant system agrees with the results obtained in previous studies after static and dynamic apnoeas (Joulia et al, 2002;Joulia et al, 2003). Increased ROS production can activate the CAT in erythrocytes (Tauler et al, 1999) and induce the synthesis of antioxidant enzymes such as SOD in lymphocytes (Khassaf et al, 2003;Tauler et al, 2003).…”

Section: Discussionsupporting

confidence: 91%

Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea

Sureda

Batle²,

Tauler

et al. 2006

Eur J Clin Nutr

View full text Add to dashboard Cite

Objective: We have investigated the influence of vitamin C diet supplementation on the antioxidant response and nitrite levels in lymphocytes and erythrocytes during diving apnea. Subjects: Seven male professional apnea divers participated in a double blind crossover study. Divers were randomly assigned to either vitamin C supplemented or placebo groups. The subjects did not take any other supplements than the ones provided for this study. Intervention: One group was supplemented with vitamin C capsules (1 g per day) for 7 days while the other group took a placebo composed of lactose. The usual dietary habits of participants were assessed using a self-reported 7-days 24-h recall before the day of the study. Blood samples were taken under basal conditions, immediately after diving apnea for 4 h and after 1 h of recovery. Results: Catalase activity increased in erythrocytes (23%) and superoxide dismutase increased in lymphocytes (35%) during the recovery only in the placebo group. Lymphocyte ascorbate levels increased in the supplemented group after diving (85%) and maintained high at recovery. Plasma nitrite levels increased about twofold in both groups during the recovery. Erythrocyte nitrite levels increased after diving (50%) and about twofold during the recovery in the supplemented group. Nitrite levels and iNOS levels in lymphocytes were higher in the placebo group than in the supplemented during the recovery. Erythrocyte carbonyl derivates were unchanged in all situations. Conclusions: Vitamin C supplementation influenced the antioxidant response and NO handling in erythrocytes and lymphocytes to the oxidative stress induced by hypoxia-reoxygenation.

show abstract

Section: Discussionsupporting

confidence: 91%

Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea

Sureda

Batle²,

Tauler

et al. 2006

Eur J Clin Nutr

View full text Add to dashboard Cite

show abstract

“…Opposite changes in the Paco 2 level occur during inhalation of the hypoxic mixture and apnea. Indeed, the apnea combines transient hypoxemia with hypercapnia, 22,23 whereas the hyperventilation elicited by the inhalation of the hypoxic gas mixture always induces hypocapnia. The Paco 2 variations may explain the opposite H-reflex changes in our two experimental conditions, in the same way that variable M-wave changes have been found in normocapnic or hypercapnic hypoxemic patients.…”

Section: Figurementioning

confidence: 99%

Effects of hypoxia on muscle response to tendon vibration in humans

Delliaux

Jammes

2006

Muscle and Nerve

Self Cite

View full text Add to dashboard Cite

Previous animal studies have shown that hypoxia markedly reduces the activation of muscle spindles. The present study was undertaken to determine whether a reduced oxygen supply to muscle affects the tonic vibration reflex (TVR) in humans. In resting healthy volunteers, the effects of inhalation of hypoxic gas, apnea, and total forearm ischemia produced by cuff inflation were studied on separate days. The TVR was recorded in flexor digitorum superficialis and the neuromuscular conduction time (CT) was measured from the compound muscle action potential; the latency and amplitude of the H reflex were also determined. TVR depression began during inhalation of the hypoxic gas, at the end of apnea, and during cuff inflation, and persisted during the recovery period. The H-reflex amplitude concomitantly increased or remained unchanged. Thus, hypoxia seems to directly alter muscle spindle reactivity. Such alterations of sensorimotor control may occur in patients suffering from respiratory or circulatory insufficiency and may contribute to their exercise limitation.

show abstract

“…For example, apnea training, as a form of hypoxic training, it arguably positively affects oxidative stress and blood acidosis [19,24] which may have a favorable impact on aquatic sports athletes' performance.…”

Section: Discussionmentioning

confidence: 99%

“…The lack of oxygen due to apnea, inevitably triggers the anaerobic metabolism causing an increase in blood lactate [13,[16][17][18]. However, apnea trained individuals exhibit reduced blood acidosis and oxidative stress which may positively affect performance [17,19]. Further, apnea triggers a temporary rise in haemoglobin which is higher in divers compared to skiers and controls [20].…”

Section: Potential Benefits Of Hypoxic Training For Aquatic Sportsmentioning

confidence: 99%

Apnea Training Specificity and its Implications for Performance in Aquatic Sports: Case Study Reports

Konstantinidou¹

2017

Int J Sports Exerc Med

View full text Add to dashboard Cite

Breath-hold training of humans reduces oxidative stress and blood acidosis after static and dynamic apnea

Cited by 69 publications

References 28 publications

Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea

Vitamin C supplementation influences the antioxidant response and nitric oxide handling of erythrocytes and lymphocytes to diving apnea

Effects of hypoxia on muscle response to tendon vibration in humans

Apnea Training Specificity and its Implications for Performance in Aquatic Sports: Case Study Reports

Contact Info

Product

Resources

About