Brevibacillus laterosporus: A Probiotic with Important Applications in Crop and Animal Production

Liu, Yucheng; Zai, Xueying; Weng, Guangying; Ma, Xianyong; Deng, Dun

doi:10.3390/microorganisms12030564

Cited by 4 publications

(1 citation statement)

References 63 publications

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“…Iurlina & Fritz, 2005 ; Panda et al., 2014 ; Sarkar et al., 2002 ). B. laterosporus is also used as a commercial probiotic, human dietary supplement and feed additive (Liu et al., 2023 ; Liu et al., 2024 ; Wang et al., 2022 ). However, the amount of Mpp75Aa1.1 protein consumption by humans and animals through exposure to B. laterosporus has not been established.…”

Section: Assessmentmentioning

confidence: 99%

Assessment of genetically modified maize MON 95275 (application GMFF‐2022‐5890)

Mullins,

Bresson,

Dalmay

et al. 2024

EFS2

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Genetically modified maize MON 95275 was developed to confer protection to certain coleopteran species. These properties were achieved by introducing the mpp75Aa1.1, vpb4Da2 and DvSnf7 expression cassettes. The molecular characterisation data and bioinformatic analyses reveal similarity to known toxins, which was further assessed. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between maize MON 95275 and its conventional counterpart needs further assessment. The GMO Panel does not identify safety concerns regarding the toxicity and allergenicity of the Mpp75Aa1.1 and Vpb4Da2 proteins and the DvSnf7 dsRNA and derived siRNAs as expressed in maize MON 95275 and finds no evidence that the genetic modification would change the overall allergenicity of maize MON 95275. In the context of this application, the consumption of food and feed from maize MON 95275 does not represent a nutritional concern in humans and animals. The GMO Panel concludes that maize MON 95275 is as safe as the conventional counterpart and non‐GM maize varieties tested, and no post‐market monitoring of food/feed is considered necessary. In the case of accidental release of maize MON 95275 material into the environment, this would not raise environmental safety concerns. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of maize MON 95275. The GMO Panel concludes that maize MON 95275 is as safe as its conventional counterpart and the tested non‐GM maize varieties with respect to potential effects on human and animal health and the environment.

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