Brewer’s spent grain as a self-sufficient feedstock for homofermentative production of optically pure L-lactic acid using Lactobacillus rhamnosus

Granget, Coralie; Manikandan, N. Arul; Amulya, K.; Dabros, Michal; Fahy, Samantha; Kelleher, Susan M.; Rochfort, Keith D.; Gaughran, Jennifer; Freeland, Brian

doi:10.1016/j.eti.2024.103582

Environmental Technology & Innovation

2024

DOI: 10.1016/j.eti.2024.103582

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Brewer’s spent grain as a self-sufficient feedstock for homofermentative production of optically pure L-lactic acid using Lactobacillus rhamnosus

Coralie Granget,

N. Arul Manikandan,

K. Amulya

et al.

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2024

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Cited by 4 publications

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Third-Generation L-Lactic Acid Biorefinery Approaches: Exploring the Viability of Macroalgae Detritus

Chong,

Tan,

Foo

et al. 2024

Bioenerg. Res.

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Rising concerns over fossil fuel depletion and plastic pollution have driven research into biodegradable alternatives, such as polylactic acid (PLA). Microbial fermentation is preferred for lactic acid production due to its ability to yield enantiomerically pure lactic acid, which is essential for PLA synthesis, unlike the racemic mixture from chemical synthesis. However, commercial lactic acid production using first-generation feedstocks faces challenges related to cost and sustainability. Macroalgae offer a promising alternative with their rapid growth rates and carbon capture capabilities. This review explores recent technological advancements in macroalgae physicochemical characterization, optimization of fermentation conditions, and innovative pretreatment methods to enhance sugar conversion rates for L-LA production. It also covers downstream processes for L-LA recovery, presenting a complete macroalgal biorefinery system. Environmental impacts and economic prospects are assessed through exergy and techno-economic analyses. By valorizing macroalgae detritus, this study underscores its potential to support a sustainable biorefinery industry, addressing economic feasibility and environmental impact.

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Third-Generation L-Lactic Acid Biorefinery Approaches: Exploring the Viability of Macroalgae Detritus

Chong,

Tan,

Foo

et al. 2024

Bioenerg. Res.

View full text Add to dashboard Cite

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Optimization of D-lactic acid biosynthesis from diverse carbon sources in mutant Lactobacillus delbrueckii subsp. bulgaricus via random mutagenesis

Mukherjee,

Pal,

Sivaprakasam

2024

Syst Microbiol and Biomanuf

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Bio-based polylactic acid labware as a sustainable alternative for microbial cultivation in life science laboratories

O Loughlin,

Herward,

Doherty

et al. 2024

Heliyon

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Brewer’s spent grain as a self-sufficient feedstock for homofermentative production of optically pure L-lactic acid using Lactobacillus rhamnosus

Cited by 4 publications

References 37 publications

Third-Generation L-Lactic Acid Biorefinery Approaches: Exploring the Viability of Macroalgae Detritus

Third-Generation L-Lactic Acid Biorefinery Approaches: Exploring the Viability of Macroalgae Detritus

Optimization of D-lactic acid biosynthesis from diverse carbon sources in mutant Lactobacillus delbrueckii subsp. bulgaricus via random mutagenesis

Bio-based polylactic acid labware as a sustainable alternative for microbial cultivation in life science laboratories

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