Brief anabolic steroid use and sustained behavioral reaction

Jj, Oh; Ta, Rummans; Mk, O'Connor; Je, Ahlskog

doi:10.1176/ajp.149.2.271b

Cited by 36 publications

(3 citation statements)

References 7 publications

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“…[ 79 ] Reports published after 1990 also have reported the beneficial effect of ECT in both symptoms of depression and PD per se. [ 80 81 ] However, these studies suggest high rates of transient inter-treatment delirium necessitating the postponement/termination. [ 80 81 ] An occasional open-label study has also evaluated the beneficial effect of cognitive behavior therapy for management of depression in patients with CBT and report significant improvement in the Hamilton Depression Rating Scale scores.…”

Section: Introductionmentioning

confidence: 99%

“…[ 80 81 ] However, these studies suggest high rates of transient inter-treatment delirium necessitating the postponement/termination. [ 80 81 ] An occasional open-label study has also evaluated the beneficial effect of cognitive behavior therapy for management of depression in patients with CBT and report significant improvement in the Hamilton Depression Rating Scale scores. [ 82 83 84 85 ] Other studies have shown that caregiver participation and executive functioning predict the response to CBT in patients with PD.…”

Section: Introductionmentioning

confidence: 99%

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Psychiatric aspects of Parkinson’s disease

Grover

Somaiya

Kumar

et al. 2015

Journal of Neurosciences in Rural Practice

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Parkinson's disease (PD) is essentially characterized by the motor symptoms in the form of resting tremor, rigidity and bradykinesia. However, over the years it has been recognized that motor symptoms are just the “tip of the iceberg” of clinical manifestations of PD. Besides motor symptoms, PD characterized by many non-motor symptoms, which include cognitive decline, psychiatric disturbances (depression, psychosis and impulse control), sleep difficulties, autonomic failures (gastrointestinal, cardiovascular, urinary, thermoregulation) and pain syndrome. This review evaluates the various aspects of psychiatric disorders including cognitive decline and sleep disturbances in patients with PD. The prevalence rate of various psychiatric disorders is high in patients with PD. In terms of risk factors, various demographic, clinical and treatment-related variables have been shown to be associated with higher risk of development of psychiatric morbidity. Evidence also suggests that the presence of psychiatric morbidity is associated with poorer outcome. Randomized controlled trials, evaluating the various pharmacological and non-pharmacological treatments for management of psychiatric morbidity in patients with PD are meager. Available evidence suggests that tricyclic antidepressants like desipramine and nortriptyline are efficacious for management of depression. Among the antipsychotics, clozapine is considered to be the best choice for management of psychosis in patients with PD. Among the various cognitive enhancers, evidence suggest efficacy of rivastigmine in management of dementia in patients with PD. To conclude, this review suggests that psychiatric morbidity is highly prevalent in patients with PD. Hence, a multidisciplinary approach must be followed to improve the overall outcome of PD. Further studies are required to evaluate the efficacy of various other measures for management of psychiatric morbidity in patients with PD.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Psychiatric aspects of Parkinson’s disease

Grover

Somaiya

Kumar

et al. 2015

Journal of Neurosciences in Rural Practice

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“…Over the years, many case reports and surveys have been presented, which indicate that the use of AAS may cause aggressive behavior [ 90 , 91 , 92 ]. Initially, people using AAS noticed increased irritability, agitation, and anger [ 93 ]. With long-term use of these compounds, loss of inhibitions, mood swings, suspiciousness, argumentativeness, impulsiveness, and aggressive behaviors [ 94 ] have been recorded, sometimes resulting in assaults on public property, self-harm, domestic violence [ 90 ], child abuse [ 95 ], suicides [ 96 , 97 ], attempted homicides, and murders [ 98 ].…”

Section: Innovative Reports On the Effects Of Aasmentioning

confidence: 99%

Innovative Reports on the Effects of Anabolic Androgenic Steroid Abuse—How to Lose Your Mind for the Love of Sport

Stojko,

Nocoń,

Piłat

et al. 2023

Medicina

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Anabolic-androgenic steroids (anabolic-androgenic steroids, AAS) are testosterone-derived compounds whose popularity and use are constantly growing. Chronic use of AAS leads to many hormonal and metabolic disorders in the human body, which often lead to permanent health damage. Changes affect the following systems: cardiovascular, musculoskeletal, reproductive, digestive, and nervous. We decided to collect the existing knowledge in the literature and enrich it with the latest research reports in the field of degenerative effects of AAS on the nervous system. The work aimed to increase public awareness of the dangers and consequences of AAS use and improve it with the latest research on the neurodegenerative effects of AAS. We hope that our work will contribute to raising public awareness and reducing the use of AAS.

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