Brief Cognitive Behavioural Therapy for Depression Associated with Parkinson's Disease: a Single Case Series

Cole, Kristina A.; Vaughan, Frances L.

doi:10.1017/s1352465804001791

Cited by 27 publications

(20 citation statements)

References 40 publications

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“…These results were also comparable to the few additional in-person CBT pilot studies for dPD conducted to date 46,48,49,50,51 and are consistent with the literature on phone-based psychotherapy for depression in other patient groups 21 . Importantly, this study provides preliminary evidence that the beneficial effects of telephone psychotherapy observed in other chronic medical conditions are not attenuated by the neuropsychiatric complexity that is characteristic of the PD population.…”

Section: Discussionsupporting

confidence: 88%

Telephone-Based Cognitive–Behavioral Therapy for Depression in Parkinson Disease

Dobkin¹,

Menza²,

Allen³

et al. 2011

J Geriatr Psychiatry Neurol

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Background Although face-to-face cognitive-behavioral therapy was found to be beneficial for the treatment of depression in Parkinson’s disease (PD) in a recent randomized-controlled trial, access to care was identified as a critical issue that needs to be addressed in order to improve the management of this non-motor complication in PD. The purpose of this study was to examine the feasibility and effect of telephone-based cognitive-behavioral therapy for depression in Parkinson’s disease. Methods Twenty-one depressed people with Parkinson’s disease participated in an NIH-sponsored uncontrolled pilot trial of telephone-based cognitive-behavioral therapy in an academic medical center from October 2009 to February 2011. The Hamilton Depression Rating Scale was the primary outcome. Treatment was provided to people with Parkinson’s disease for 10 weeks, modified for delivery over the phone, and supplemented with 4 separate phone-based caregiver educational sessions. Assessments were completed at baseline and 5 (midpoint), 10 (end-of-treatment), and 14 weeks (follow-up) post-enrollment. Results Twenty (95%) people with Parkinson’s disease completed the study treatment. Phone-based cognitive-behavioral therapy was associated with significant improvements in depression, anxiety, negative thoughts, and coping. Mean Hamilton Depression Rating Scale change from baseline to week 10 was 7.91 points (P<.001, Cohen’s d=1.21). Conclusions Telephone-based cognitive-behavioral therapy may be a feasible and helpful approach for treating depression in Parkinson’s disease and warrants further exploration in randomized-controlled trials. Results were comparable to those observed in the few in-person cognitive-behavioral treatment studies for depression in Parkinson’s disease conducted to date.

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Section: Discussionsupporting

confidence: 88%

Telephone-Based Cognitive–Behavioral Therapy for Depression in Parkinson Disease

Dobkin¹,

Menza²,

Allen³

et al. 2011

J Geriatr Psychiatry Neurol

View full text Add to dashboard Cite

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“…Two studies using single‐case experimental design methodology reported efficacy of CBT for anxiety and depression in PD. Cole and Vaughan reported on 5 individuals with PD and depression who received 7 sessions of CBT. Four of the 5 patients were considered recovered on depression on the GDS at 1‐month follow‐up.…”

Section: Efficacy Of Cbt For Depression and Anxiety In Pdmentioning

confidence: 99%

Clinical issues in the treatment of anxiety and depression in older adults with Parkinson's disease

et al. 2013

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A significant proportion of persons affected by Parkinson's disease (PD) are over age 65 years. Mental health issues are often less a focus of treatment in this population than physical manifestations of the illness. Anxiety or depression alone, as well as comorbid depression and anxiety, are underrecognized in patients with PD and are associated with deleterious effects on physical and interpersonal functioning, negatively impacting quality of life and well-being. We offer a brief overview of salient clinical points with respect to assessment and treatment approaches to enhance efficacy of the treatment of mental health symptoms in older adults with PD. Cognitive behavior therapy involves the patient learning to overcome behavioral avoidance associated with anxiety and challenge unhelpful negative cognitions. It is suggested that cognitive behavior therapy is an effective approach to treatment of anxiety and depression in PD and should be offered as a treatment to patients.

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“…As participants were not randomly assigned to treatment condition, endorsed very mild depressive symptoms at baseline, and had comparison groups that were unequal in size, only very limited conclusions may be drawn from this study [51]. An uncontrolled 15-patient pilot study [52] and several case reports have also documented the feasibility of CBT for dPD [53,54]. Moreover, an eightsession group educational program for PD patients and their caregivers that introduced many of the skills covered in CBT, such as self-monitoring, stress management, dealing with negative thoughts, and appropriate use of social supports, was pilot tested with 36 participants [55].…”

Section: Depression and Parkinson's Diseasementioning

confidence: 99%

CBT for the treatment of depression in Parkinson’s disease: a promising nonpharmacological approach

Dobkin¹,

Menza²,

Bienfait³

2008

Expert Review of Neurotherapeutics

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Depression is very common in PD and linked with a faster progression of physical symptoms, greater cognitive decline, and poorer quality of life. Non-pharmacological approaches, like cognitivebehavioral therapy (CBT), for the treatment of depression in Parkinson's disease (dPD) have received little experimental attention despite strong demonstrated efficacy in other geriatric and medical populations. Depressed PD patients often differ from the depressed non-PD elderly in that they present with increased rates of both executive dysfunction and co-morbid psychiatric diagnoses, may differ in their depressive symptom presentation, and typically have caregivers who are highly involved in their treatment. Therefore, it is not possible to conclude that empirically validated treatments in the depressed aged will generalize to those with Parkinson's disease. In order to be most effective for PD patients, CBT should be tailored to their unique needs. Additional controlled research is needed to further explore the efficacy of CBT for dPD.

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Brief Cognitive Behavioural Therapy for Depression Associated with Parkinson's Disease: a Single Case Series

Cited by 27 publications

References 40 publications

Telephone-Based Cognitive–Behavioral Therapy for Depression in Parkinson Disease

Telephone-Based Cognitive–Behavioral Therapy for Depression in Parkinson Disease

Clinical issues in the treatment of anxiety and depression in older adults with Parkinson's disease

CBT for the treatment of depression in Parkinson’s disease: a promising nonpharmacological approach

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