There has been a substantial increase in autism spectrum disorder (ASD) research over the last decade. An important advancement in this research has been in the study of well-being in people with ASD. The purpose of the current study was to examine the deficit and strength foci of wellbeing research in the field. One thousand one hundred and fifty-four articles were randomly selected across five major ASD journals over an 11-year period and were coded for a focus on well-being, perspective (deficits, strengths, or mixed), intervention or non-intervention study, topic area, and methodology. Approximately 37% (n = 431) of articles focused on well-being of people with ASD. Half of these studies had a deficits perspective (50.3%), 11% had a strengths perspective, while the rest were mixed (i.e. both deficits-and strengths-focused). Roughly 41% of well-being articles were intervention studies. Approximately 58% of strengths-and mixed-focused articles included a focus on a strength construct (e.g. positive affect, self-determination). The current study provides a foundation for future strengthsfocused work, which is essential to our understanding of wellbeing and positive functioning. Findings highlight trends with respect to the focus on strengths in ASD research, which may have important implications on positive conceptualizations of ASD and future strengths-focused research and practice.