Brief review of parathyroid adenoma; problems caused by water clear cells

Abstract

Water clear cells; they can be seen in many tumors such as germ cell tumors, kidney tumors, lymphomas, sarcomas, thymic carcinomas, parathyroid carcinomas, paraganglioma. They may be primary or may occur as a result of metastatic conditions. Therefore, histopathologically differential diagnosis may be difficult or confusing. Clinical findings, radiological findings and histopathological evaluation may be required for differential diagnosis. Here, as immunohistochemically; a case with parathormone, CD10 positive and synaptophysin negative and CD10 positivity in the area where clear cells are dominant is presented.The case was reported as water clear cell (WCC) component dominant parathyroid adenoma with clinical, biochemical, radiological evaluation and histopathology and the differential diagnosis is discussed.