British Association of Dermatologists guidelines for the management of people with rosacea 2021*

Hampton, Philip; Berth‐Jones, J.; Williamson, C.E. Duarte; Hay, Roderick J.; Leslie, Tabi A.; Porter, Ian; Rauz, Saaeha; Seukeran, D.C.; Winn, R T; Hashme, M; Exton, L.S.; Mustapa, M.F. Mohd; Manounah, L

doi:10.1111/bjd.20485

Cited by 26 publications

(16 citation statements)

References 49 publications

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“…The mean duration of treatment with oral antibiotics was 52 days during 2013–2018 and was increased by 10 days in 2007–2017. The treatment guidelines recommend 4–8 weeks of antibiotics for rosacea [ 17 , 18 , 19 , 20 ], and our overall course of antibiotic use for rosacea is in line with these guidelines. Although oral antibiotics are the treatment of choice for the papulopustular skin lesions of rosacea, long-term use of antibiotics can result in antibiotic resistance [ 21 ].…”

Section: Discussionmentioning

confidence: 92%

Patient Visits and Prescribing Patterns Associated with Rosacea in Korea: A Real-World Retrospective Study Based on Electronic Medical Records

Woo

Bae³

et al. 2022

JCM

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Rosacea is a common and chronic inflammatory skin disorder. The visiting trends and prescribing patterns involving Korean patients with rosacea have not been thoroughly examined. To examine the visiting trends of patients with rosacea, and to analyze the prescription patterns of Korean dermatologists managing such patients, a retrospective cross-sectional study on dermatology outpatients who visited the seven affiliated hospitals of The Catholic University of Korea between 2007 and 2018 was performed. A total of 56,651 visits were made by rosacea patients. The mean annual number of hospital visits made by rosacea patients over a 6-year period increased from 2456 in 2007–2012 to 6985 in 2013–2018. Hospital visits were most prevalent in female patients aged 40 to 59 years. There was no statistically significant difference in patient visitation between the seasons. As for prescriptions, systemic antibiotics were most commonly prescribed, followed by antihistamines, non-steroidal anti-inflammatory drugs, and retinoids. Among the topical agents, metronidazole was the most prescribed agent during 2007–2012, whereas calcineurin inhibitors were favored most during 2013–2018. Dermatology outpatient visits by individuals with rosacea have increased in Korea over time. The real-world prescription trend presented here may help dermatologists facilitate better treatment strategies and provide appropriate guidance to patients with rosacea.

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Section: Discussionmentioning

confidence: 92%

Patient Visits and Prescribing Patterns Associated with Rosacea in Korea: A Real-World Retrospective Study Based on Electronic Medical Records

Woo

Bae³

et al. 2022

JCM

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“…It can also be accompanied by eye symptoms such as conjunctivitis, blepharitis, irritation, and dryness. Most patients have erythema and flushing 3 . The pathogenesis of rosacea is complex.…”

Section: Introductionmentioning

confidence: 99%

“…Most patients have erythema and flushing. 3 The pathogenesis of rosacea is complex. At present, it is considered to be related to genetic factors, imbalance of congenital and adaptive immune system, neurovascular dysfunction, and hair follicle Demodex.…”

mentioning

confidence: 99%

A randomized, controlled, split‐face study of botulinum toxin and broadband light for the treatment of erythematotelangiectatic rosacea

Tong

Luo

Gao

et al. 2022

Dermatologic Therapy

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To study the efficacy and safety of botulinum toxin (BTX) combined with broadband light (BBL) in the treatment of rosacea‐related erythema and flushing. A randomized, single‐blind, split‐face controlled study including 22 patients with erythemato telangiectatic rosacea were enrolled. Both cheeks were randomly divided into experimental group and control group. They were treated three times with an interval of 1 month. In the first treatment, the experimental group received BBL treatment and intradermal injection of BTX, and the control group received BBL treatment and intradermal injection of the same amount of normal saline; in the second and third treatments were both groups received the same BBL treatment. The patients were evaluated before the first treatment and 1, 2, 3, and 6 months after the treatment. Compared with the control group, the hydration in the experimental group increased and the global flushing symptom score (GFSS), VISIA red value, erythema index, transepidermal water loss, and sebum secretion decreased. The differences were statistically significant (p < 0.05). In the experimental group, at 3 months after the first treatment, compared with before treatment, the GFSS, VISIA red value, erythema index, transepidermal water loss and sebum secretion decreased the hydration increased. The sebum secretion returned to the pretreatment level in 6 months after treatment, and the other indexes maintained the level in 3 months after treatment. One patient had a slight lifting limitation of the corners of his mouth after 10 days of BTX injection, without special treatment, and recovered after 1 month. BTX intradermal injection combined with BBL has a definite therapeutic effect on the improvement of rosacea related erythema and flushing, which is better than simple BBL, and has high safety. It is worthy of clinical promotion.

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“…[ 4 ] Nevertheless, guidelines for the management of rosacea produced by the British Association of Dermatologists that recommended the older rosacea classification system, containing erythematotelangiectatic (ETR), papulopustular (PPR), phymatous (PHR), and ocular characterized by clinical signs, should also be taken into account. [ 5 ] Moreover, in clinical practice guidelines and consensus of several countries, therapeutic regimens are still guided by the four main rosacea subtypes. [ 3 , 6 , 7 ] Therefore, an appropriate classification is essential to improve the patients’ prognoses.…”

Section: Introductionmentioning

confidence: 99%

Summarization and comparison of dermoscopic features on different subtypes of rosacea

Fei

Han

et al. 2022

Chinese Medical Journal

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Background: The dermoscopic features of rosacea have already been reported. However, the current findings are incomplete, and little is known about phymatous rosacea. Hence, this study aimed to summarize and compare the dermoscopic features and patterns of three rosacea subtypes (erythematotelangiectatic [ETR], papulopustular [PPR], and phymatous [PHR]) in the Chinese Han population and to evaluate whether these features differ with patients’ genders, ages, and durations. Methods: Dermoscopic images of 87 rosacea patients were collected in non-polarized and polarized dermoscopy contact modes at 20-fold magnification. Dermoscopic features, including vessels, scales, follicular findings, and other structures, were summarized and evaluated. Results: The reticular linear vessels and red diffuse structureless areas of ETR were distinctive. For PPR, red diffuse structureless areas, reticular linear vessels, yellow scales, follicular plugs, and follicular pustules were typical dermoscopic criteria. The common dermoscopic features of PHR were: orange diffuse structureless areas, linear vessels with branches, perifollicular white color, orange focal structureless areas, and white lines. The following features statistically differed among the three rosacea subtypes: reticular linear vessels ( P < 0.001), unspecific linear vessels ( P = 0.005), linear vessels with branches ( P < 0.001), yellow scales ( P = 0.001), follicular plugs ( P < 0.001), perifollicular white color ( P < 0.001), red diffuse structureless areas ( P = 0.022), orange diffuse structureless areas ( P < 0.001), red focal structureless areas ( P = 0.002), orange focal structureless areas ( P = 0.003), white lines ( P < 0.001), follicular pustules ( P < 0.001), and black vellus hairs ( P < 0.001). Conclusions: The dermoscopic patterns of ETR are red diffuse structureless areas and reticular linear vessels. For PPR, the pattern comprehends combinations of red diffuse structureless areas, reticular linear vessels, yellow scales, follicular plugs, and follicular pustules. Meanwhile, PHR is characterized by remarkable orange diffuse structureless areas, linear vessels with branches, perifollicular white color, orange focal structureless areas, and white lines.

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British Association of Dermatologists guidelines for the management of people with rosacea 2021*

Cited by 26 publications

References 49 publications

Patient Visits and Prescribing Patterns Associated with Rosacea in Korea: A Real-World Retrospective Study Based on Electronic Medical Records

Patient Visits and Prescribing Patterns Associated with Rosacea in Korea: A Real-World Retrospective Study Based on Electronic Medical Records

A randomized, controlled, split‐face study of botulinum toxin and broadband light for the treatment of erythematotelangiectatic rosacea

Summarization and comparison of dermoscopic features on different subtypes of rosacea

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