Broad Spectrum Antifungal Properties of the Lichen Heterodermia leucomela

Shahi, Sushil Kumar; Shukla, Amritesh C.; Dikshit, Anupam; Uperti, D.K.

doi:10.1006/lich.2000.0303

Cited by 21 publications

(36 citation statements)

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“…Established results on the antifungal activity of Everniastrum cirrhatum with minimum fungicidal concentration (MFC) of as low as 60 μ L/mL against human pathogenic fungi (dermatophytes), namely, Epidermophyton floccosum, Microsporum gypseum, M. canis, M. audounii, Trichophyton rubrum, T. mentagrophytes, T. violaceum, and T. tonsurans, have also been reported in the past [33]. Heterodermia leucomelos was also found effective against human as well as plant pathogenic fungi [34]. Some macrolichens extracts, namely, Parmelia tinctorum, Ramalina sp., Teloschistes flavicans, and Usnea undulata , were tested and found effective against some pathogenic fungi [35].…”

Section: Resultsmentioning

confidence: 99%

Management of Cosmetic Embarrassment Caused byMalasseziaspp. with Fruticose LichenCladiaUsing Phylogenetic Approach

Pandey

Mishra

Tiwari

et al. 2013

BioMed Research International

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During anti-Malassezia screening of plants by CLSI broth microdilution method, Cladia aggregata (Swartz) Nyl. (family Cladoniaceae), a fruticose lichen from Sikkim (northeast Himalayan region), has been found effective at minimum inhibitory concentrations (mg/mL) of 2.72, 0.63, and 1.28 against yeast-like fungi namely, M. furfur, M. globosa and M. sympodialis, respectively. These test pathogens are responsible for pityriasis versicolor (PV) and seborrheic dermatitis (SD) in humans. We tried to establish the reason for variable MICs against various Malassezia spp. using bioinformatical tools, thereby reducing the cost of the experimentation. This is the first report on anti-Malassezia activity of C. aggregata and thus can serve as a potential source for the development of cosmaceuticals.

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Section: Resultsmentioning

confidence: 99%

Management of Cosmetic Embarrassment Caused byMalasseziaspp. with Fruticose LichenCladiaUsing Phylogenetic Approach

Pandey

Mishra

Tiwari

et al. 2013

BioMed Research International

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“…Fungal diseases of plants result in decreased [ [42][43][44][45][46][47][48] In this study, we evaluated antifungal potential of two concentrations of an extract of H. incana, viz., 0.5 mg/ml and 1 mg/ml by poisoned food technique. Poisoning of medium with extract resulted in drastic reduction in mycelial growth of test fungi [ Table 3 and Figure 3].…”

Section: Antibacterial Activity Of H Incanamentioning

confidence: 99%

“…was 78.26%, 76.60%, and 68.77%, respectively [ Figure 4]. Earlier studies have shown the potential of some Heterodermia species such as H. boryi, [15] H. diademata, [36,49] H. comosa, [50] H. leucomelos, [42,51] H. microphylla, [43] and H. obscurata [8] to inhibit phytopathogenic fungi.…”

Section: Antibacterial Activity Of H Incanamentioning

confidence: 99%

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2017

IJGP

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Objectives: Lichens represent one of the most successful symbiotic interactions and are formed from a photobiont and a mycobiont. The foliose lichen genus Heterodermia is one of the cosmopolitan lichen genera. The present study was conducted to investigate antibacterial and antifungal activity of Heterodermia incana (Stirt.) D.D. Awasthi, a foliose macrolichen belonging to the family Physciaceae. Materials and Methods: Extraction of dried and powdered lichen was carried out by maceration process. Antibacterial activity of the extract was evaluated against 2 Gram-positive and 2 Gram-negative bacteria by agar well diffusion assay. Antifungal activity of extract was determined against 3 seedborne fungi by poisoned food technique. Results: Extract was effective in inhibiting the growth of all test bacteria in a concentration dependent manner with marked activity against Gram-positive bacteria. Bacillus cereus (zone of inhibition 2.26 ± 0.05 cm) and Pseudomonas aeruginosa (zone of inhibition 1.76 ± 0.05 cm) were inhibited to higher extent among Gram-positive and Gram-negative bacteria, respectively, at 10 mg/ml extract concentration. The extract was effective in inhibiting the mycelial growth of test fungi in a concentration dependent manner. Among three fungi, the susceptibility to extract was in the order: Fusarium sp. > Curvularia sp. > Alternaria sp. At extract concentration 1 mg/ml, >60% inhibition of all test fungi was observed. Conclusion:The lichen H. incana is a promising resource of antimicrobial agents. The observed bioactivities could be attributed to the presence of secondary metabolites such as atranorin and zeorin present in the extract. In suitable form, the lichen can be used as anti-infective agent and in the management of seedborne fungal diseases.

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“…Otro hongo liquenizado con una marcada actividad fungicida fue Parmelia sulcata, que en dosis bajas (0,0037 mg/ml), inhibió el crecimiento de Fusarium oxysporum, Botritis cinérea y Aspergillus fumigatus (Rankovic y Kosanic, 2012). Por otra parte, Shahi et al (2001) utilizaron el extracto acuoso de Heterodermia leucomela obteniendo efecto de un 100% de inhibición a dosis de 60 y 80 µl/ml, sobre los hongos fitopatógenos Cladosporium gladosporioides, Curvularia lunata y Fusarium oxysporum. Los resultados obtenidos en la clasificación de los extractos liquénicos sobre P. nicotianae y R. solani pueden variar de acuerdo a las dosis establecidas para el estudio, por lo que se podrían analizar con otras concentraciones mayores.…”

Section: Porcentajes De Inhibición Del Crecimiento Micelialunclassified

Actividad antifúngica de extractos de tres especies de líquenes en Cuba.

et al. 2015

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El objetivo del presente estudio fue evaluar la actividad fungicida de los extractos de tres especies de líquenes. De las especies Leptogium cyanescens, Physcia americana y Pyxine aff. cocoes fueron colectados extractos del talo liquénico en el año 2009, en áreas del Jardín Botánico de Cienfuegos, Cuba. La actividad fungicida fue evaluada en hongos fitopatógenos de papa; Rhizoctonia solani y Phytophthora nicotianae var parasitica. El estudio se realizó en el periodo comprendido del 2009-2011. Los compuestos se extrajeron con acetona, se concentraron por rotoevaporación, y se evaluaron a concentraciones de 0,01 y 0,07% en medio de cultivo agar papa dextrosa (PDA), para lo cual se preparó una solución madre al 5% en dimetisufóxido. Los extractos se clasificaron por su toxicidad como: tóxico, ligero y moderadamente tóxico e inocuo. El extracto de P. americana al 0,07% inhibió 100% a P. nicotianae, y frente a R. solani manifestó valores por encima de 50%. L. cyanescens solo mostró actividad fungicida en ambos fitopatógenos a la mayor concentración estudiada; resultados similares se obtuvieron con el extracto de P. aff. cocoes. Los extractos liquénicos se clasificaron como ligeramente tóxicos a la mayor concentración e inocuos a la menor concentración probada.

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Broad Spectrum Antifungal Properties of the Lichen Heterodermia leucomela

Cited by 21 publications

References 4 publications

Management of Cosmetic Embarrassment Caused byMalasseziaspp. with Fruticose LichenCladiaUsing Phylogenetic Approach

Management of Cosmetic Embarrassment Caused byMalasseziaspp. with Fruticose LichenCladiaUsing Phylogenetic Approach

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Actividad antifúngica de extractos de tres especies de líquenes en Cuba.

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