Broad-Spectrum Antimicrobial Polymer with Dual Bactericidal Mechanisms Enhances Antibiotic Activity in the Treatment of Fish Infections
Yue Yu,
Xianhui Chen,
Huangsheng Pu
et al.
Abstract:Bacterial infection in aquaculture farming has been a well-known issue, and the situation is worsened by the limitations on antibiotic usage due to environmental considerations. This study reports the design and synthesis of a broad-spectrum antimicrobial polymer, P C3−8 , demonstrated for the first time as an efficient antimicrobial agent against a number of common fish pathogens, including Gram-positive and Gram-negative ones. A dual-bactericidal mechanism is proposed for P C3−8 , in which the cationic polym… Show more
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