Bromination of Trifluoromethylbenzenes

A Study of the Chlorination of Methylchlorosilanes

“…The peroxide catalyzed chlorination of trimethyichlorosilane and ¿-butyl chloride was later studied by McBride and Beachell. 3 The observations of Krieble and Elliott have been confirmed in this Laboratory during several years and further data concerning the anomalies found during the chlorination of methylsilicon compounds were obtained. Very interesting results have been found which shed new light on the role of silicon in organosilicon compounds during chlorination.…”

Bromine Chloride: an Alternative to Bromine

“…As a result of its polarity, BrCl will undergo some reactions that do not take place with bromine. When reactions do occur, + HCI (Speier, 1951) Low yields (McBee et al, 1950) BrCl CF3…”

Neurotropic and psychotropic agents. LXVII. 1-[4,4-Bis(4-fluorophenyl)butyl]-4-hydroxy-4-(3-trifluoromethyl-4-chlorophenyl)piperidine and related compounds: New synthetic approaches

“…Ref. 19 gives for a product obtained by bromination of 2-chlorobenzotrifluoride in the presence of chlorine and antimony pentachloride, a b.p. of 197-198°C/ 740 Torr.…”

“…Preparation of the starting 2-chloro-5-bromobenzotrifluoride (XXXV) has been described so far 19 only through a bromination of 2-chlorobenzotrifluoride 20 in the presence of chlorine and antimony pentachloride. It was observed that the bromination can be conducted with a fine yield under catalysis with iron.…”