“…Chronic lung diseases are found by chest X-ray or at autopsy in the majority of patients maintained on non-transplant renal replacement therapies [3,20,25]. Numerous changes in pulmonary function, including restriction [17,26], obstruction [2,7,8] and impaired diffusion capacity [11], have been described in this patient population. These pulmonary dysfunctions may be caused directly by an underlying primary pulmonary disease or the high incidence of smoking, but the influence of uremia and the effects of dialysis treatment with the artificial kidney are not well characterized [15].…”