Bronchiolar adenoma-like tumour with monolayered component: Represent malignant transformation of bronchiolar adenoma? A series of five cases

Lin, Dongliang; Li, Ding; Shao, Shihong; Xin, Fang-Jie; Zhang, Longxiao; Li, Guangqi; Zhao, Peng

doi:10.1016/j.prp.2022.154079

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…When strictly defined, classical examples of BA/CMPT seem to have a benign clinical course 1,3,4 . However, several reports now exist in the literature describing malignant transformation 7–9 . It is not clear if these reports represent collision tumours of BA/CMPT and adenocarcinoma, true malignant degeneration in BA/CMPT or adenocarcinoma closely morphologically mimicking CMPT.…”

Section: Pulmonary Adenomasmentioning

confidence: 99%

“…1,3,4 However, several reports now exist in the literature describing malignant transformation. [7][8][9] It is not clear if these reports represent collision tumours of BA/ CMPT and adenocarcinoma, true malignant degeneration in BA/CMPT or adenocarcinoma closely morphologically mimicking CMPT. Regardless, strict diagnostic criteria should be used for BA/CMPT, including clear demonstration of a basal cell layer throughout the lesion and absence of significant nuclear atypia, to avoid misclassifying an adenocarcinoma as BA/CMPT.…”

Section: Pulmonary Adenomas B R O N C H I O L a R A D E N O M A / C I...mentioning

confidence: 99%

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What's new in benign lung tumours?

Boland

2023

Histopathology

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While lung cancer is one of the most common malignancies routinely encountered by pathologists, benign pulmonary neoplasms are quite rare. However, it is important for pathologists to be familiar with the typical diagnostic features of benign lung tumors to avoid confusing them with malignant morphological mimics. There have also been intriguing discoveries in the genetics of benign pulmonary neoplasms in the past decade. This review will cover several of the most common benign lung tumors, including the diagnostic categories of pulmonary adenomas, bronchial papillomas, and benign mesenchymal tumors, with discussion of the current classification, differential diagnosis, and current knowledge regarding genetic drivers.

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Section: Pulmonary Adenomasmentioning

confidence: 99%