Bronchiolitis obliterans organising pneumonia simulating bronchial carcinoma

Murphy, Joseph; Schnyder, P.; Herold, Christian; Flower, C. D. R.

doi:10.1007/s003300050527

Cited by 33 publications

(19 citation statements)

References 16 publications

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“…Hemoptysis was also described in 3 cases with solitary nodules out of 16 patients in the series of Cordier et al [12], in only 1 of 78 patients in the series of Cazzato et al [9], and in 10 of 70 patients in the series of Lohr et al [8]. In addition to these studies, hemoptysis was reported in 3 cases with cavitating nodules out of 5 patients with solitary BOOP [17]. However, the quantity of blood was not described in these patients.…”

Section: Discussionmentioning

confidence: 94%

Bronchiolitis obliterans Organizing Pneumonia

Oymak

Demirbaş

Mavili³

et al. 2005

Respiration

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Background: Bronchiolitis obliterans organizing pneumonia (BOOP) may be classified as cryptogenic (idiopathic) and secondary. There are no clear clinical and radiological features distinguishing between idiopathic and secondary BOOP. Objectives: To analyze the etiologic factors, clinical and radiological features, diagnostic approach and response to therapy at onset and outcome in subjects with BOOP. Methods: The medical files of Erciyes University Hospital from 1995 to 2003 were retrospectively reviewed. Patients with biopsy-proven BOOP were selected for evaluation. The etiology and initial features of BOOP, treatment, resolution, relapse, and survival were obtained from medical records, and a follow-up patient questionnaire. Results: We have diagnosed 26 cases (13 males /13 females) with BOOP syndrome (mean age 54 ± 15 years, range 14–93). More than half the patients (58%) were classified as idiopathic BOOP. Patients presented with cough (92%), dyspnea (70%), pleuritic chest pain, hemoptysis and fever (50%). The biopsy specimens had been obtained by transbronchial and/or transthoracic lung biopsy in 18 cases (69%). At radiological evaluation, there were bilateral patchy alveolar and/or interstitial infiltrates in 16 patients (62%), and solitary pneumonic involvement in 10 patients (38%). Three patients recovered spontaneously, 5 remained cured after resection of the focal lesion. Corticosteroid therapy was given in 17 patients (65%). Apart from four patients who died (death was attributable to BOOP in only 1 patient) and three patients who relapsed, the prognosis was good in all patients. Conclusions: The etiology of BOOP is usually idiopathic. We observed that hemoptysis and pleuritic chest pain were a relatively frequent symptom in BOOP in the present series, in contrast to previous observations. The diversity of radiological and clinical presentations including hemotysis and pleuritic chest pain should prompt consideration of the diagnosis in patients with persisting pulmonary symptoms and radiological findings.

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Section: Discussionmentioning

confidence: 94%

Bronchiolitis obliterans Organizing Pneumonia

Oymak

Demirbaş

Mavili³

et al. 2005

Respiration

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“…This category accounted for one-third of the study group and is noteworthy that the location in 4 of 5 patients was in the upper lobes, the commonest site for lung cancer. The patient's symptoms may also suggest the diagnosis of lung cancer as focal organizing pneumonia may present with haemoptysis [70,71,72]. Occasional cavitation of focal organizing pneumonia raises the question of whether such lesions are in fact sterile post-infective or post-infarctive abscesses.…”

Section: Focal Lesionmentioning

confidence: 95%

Organizing pneumonia: the many morphological faces

2001

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Organizing pneumonia is a non-specific response to various forms of lung injury and is the pathological hallmark of the distinct clinical entity termed cryptogenic organizing pneumonia. The typical imaging features of this syndrome have been widely documented and consist of patchy air-space consolidation, often subpleural, with or without ground-glass opacities. The purpose of this article is to highlight the less familiar imaging patterns of organizing pneumonia which include focal organizing pneumonia, a variety of nodular patterns, a bronchocentric distribution, band-like opacities, a perilobular pattern and a progressive fibrotic form of organizing pneumonia.

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“…This disorder, which is a pathological diagnosis, may be triggered by drug or toxin exposure, autoimmune diseases, viral infections, or radiation injury but is most often idiopathic (272). Patients with bronchiolitis obliterans organizing pneumonia usually present with fever, cough, weight loss, and dyspnea over weeks to months, similar to many infectious diseases associated with lung cavities (76).…”

Section: Miscellaneous Diseases Associated With Cavitiesmentioning

confidence: 99%

Cavitary Pulmonary Disease

2008

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SUMMARY A pulmonary cavity is a gas-filled area of the lung in the center of a nodule or area of consolidation and may be clinically observed by use of plain chest radiography or computed tomography. Cavities are present in a wide variety of infectious and noninfectious processes. This review discusses the differential diagnosis of pathological processes associated with lung cavities, focusing on infections associated with lung cavities. The goal is to provide the clinician and clinical microbiologist with an overview of the diseases most commonly associated with lung cavities, with attention to the epidemiology and clinical characteristics of the host.

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Bronchiolitis obliterans organising pneumonia simulating bronchial carcinoma

Cited by 33 publications

References 16 publications

Bronchiolitis obliterans Organizing Pneumonia

Bronchiolitis obliterans Organizing Pneumonia

Organizing pneumonia: the many morphological faces

Cavitary Pulmonary Disease

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