Bronchoalveolar Lavage

Zhang, Wei; Huang, Yann-Chang; Helmers, Richard A.

doi:10.1002/9781119389231.ch14

Cited by 3 publications

(7 citation statements)

References 185 publications

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“…25 Similarly, a study by Zhang, et al (2020) compared the diagnostic accuracy of virtual bronchoscopic navigation (VBN) and radial probe endobronchial ultrasound (RP-EBUS) for the diagnosis of peripheral pulmonary lesions and found that VBN had a higher diagnostic yield (92.1%) than RP-EBUS (81.6%). 18 These findings suggest that new bronchoscopic technologies may improve the diagnostic accuracy and yield for lung cancer detection.…”

Section: Discussionmentioning

confidence: 97%

“…The diagnostic yield is significantly higher in diffuse disease processes that spread through lymphatic or lepidic growth, such as bronchoalveolar cell carcinoma (BAC) and adenocarcinoma. 6,18 Rao, et al as cited by Błach, et al (2021), evaluated the efficiency of bronchial wash cytology in diagnosing bronchopulmonary lesions and classifying dysplastic/malignant lesions. The technique of bronchial wash cytology showed high specificity and cytohistopathology correlation, revealing a concordance rate of 62.06%.…”

Section: Discussionmentioning

confidence: 99%

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Pathological Characteristics of Fiberoptic Bronchoscopy Procedure in Ulin General Hospital, Banjarmasin

Nurrasyidah,

Nuzula,

Oktaviyanti

et al. 2023

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Introduction: Fiberoptic Bronchoscopy (FOB) has emerged into the method of choice for the detection of lung tumors due to its availability of Adequate cytological and histological samples in the form of broncho-alveolar lavage, bronchial brushings, and bronchial forceps biopsy. This study aims to identify characteristics of bronchoalveolar lavage, aspiration cytology, brushing cytology and forceps cytology of patients suspected with malignancy at the Ulin Regional Hospital in South Kalimantan. Methods: A cross-sectional study was carried out utilizing medical documentation of patients suspested lung cancer from March 2018 to March 2020. Data were grouped by gender, age, type of procedure, and cytology and histopathology findings. Results: The result showed that 67.5% of 117 patients who underwent bronchoscopy had positive results and common histological diagnosis The frequent histopathological conclusion was adenocarcinoma (45.6%) tailed by squamous cell carcinoma (40.55). Forceps bronchoscopy showed a greater positivity rate (75.0%) than bronchoscopy without forceps (63.6%), we also found that by combining BAL and brushing and forceps biopsy, the detection rate of lung malignancy increased to 85.7%, but no correlation between the type of procedure and the likelihood of malignancy was discovered. Conclusions: Forceps bronchoscopy showed a greater positivity rate than bronchoscopy without forceps, but no correlation between the type of procedure and the likelihood of malignancy was discovered in our study.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Pathological Characteristics of Fiberoptic Bronchoscopy Procedure in Ulin General Hospital, Banjarmasin

Nurrasyidah,

Nuzula,

Oktaviyanti

et al. 2023

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“…The distinction between BAL and bronchial wash lies in the volume of normal saline used, ranging from 100-300 mL by streaming 20-50 mL several times in multiple bronchial branches, which later collected in a mucus extractor and its aliquot is subtracted to be analyzed. 11,12 Both procedures are diagnostic methods for identifying the coinfection of microorganisms in COVID-19 pneumonia to establish definitive antibiotic therapy and improve the patient's prognosis. 4 13 Diagnosis of COVID-19-associated pulmonary aspergillosis is obtained through culture and measurement of galactomannan level of BAL with a positivity rate of 55-61%.…”

Section: Indication and Objective Of Ffb In Patients With Covid-19mentioning

confidence: 99%

Preparation and Findings in Diagnostic and Therapeutic Flexible Fiberoptic Bronchoscopy Procedures in Patients with COVID-19

Pratomo

Baskoro

Soehardiman

et al. 2023

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The coronavirus disease 2019 (COVID-19), which has raised concerns about infection control for every clinical procedure, including flexible fiberoptic bronchoscopy (FFB), has drawn the attention of clinicians across the globe. A pulmonologist frequently conducts this procedure to diagnose and treat pulmonary diseases like COVID-19. This procedure involves direct airway observation and generates aerosol from the patient. However, it is considered a double-edged sword, as the risk of infection and instrument contamination always haunts its clinical benefit to the patients and the operators. Therefore, a guideline for preparing and indicating FFB in COVID-19 must be addressed appropriately by emphasizing the importance of infection prevention and control. Fortunately, several recommendations and findings have emerged over the past three years, which should support safe FFB procedures for its operators with controlled infection. This study summarizes the indication, objective, contraindication, risk, preparation, and findings in diagnostic and therapeutic FFB patients with COVID-19.

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“…Three techniques have been described for aspirating the BAL fluid, namely wall mount suction (WMS), manual suction (MS), and manual suction with tubing (MST) 8–11 . Wall suction is performed by applying negative pressure using continuous wall suction 2,8 . MS is performed by gently applying the negative pressure by pulling the plunger of a 50 mL syringe 8,11 .…”

mentioning

confidence: 99%

“…BAL has a high diagnostic value and is a crucial research tool for various lung diseases, including infections, malignancy, diffuse parenchymal lung diseases (DPLDs), and others. 1,2 The typical BAL fluid cellular components comprise alveolar macrophages 85%, lymphocytes 5% to 15%, neutrophils ≤ 3%, and eosinophils < 1%. 3,4 The presence of squamous epithelial cells indicates contamination by oropharyngeal secretions.…”

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confidence: 99%

A Randomized Control Trial Comparing the Yield of Bronchoalveolar Lavage Using Three Different Techniques in Patients Undergoing Flexible Bronchoscopy (BAL-3T)

Sehgal,

Kaur,

Gupta

et al. 2024

Journal of Bronchology &Amp; Interventional Pulmonology

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Background: Three techniques have been described for aspirating the bronchoalveolar lavage (BAL) fluid, namely the wall mount suction (WMS), manual suction (MS), and manual suction with tubing (MST). However, there is no direct comparison among the 3 methods. Methods: We randomized patients undergoing flexible bronchoscopy and BAL in a 1:1:1 ratio to one of the 3 arms. The primary outcome was to compare the optimal yield, defined as at least 30% return of volume instilled and <5% bronchial cells. The key secondary outcomes were the percentage of volume and total amount (in millimeters) return of BAL, as well as complications (hypoxemia, airway bleeding, and others). Results: We randomized 942 patients [MST (n = 314), MS (n = 314), WMS (n = 314)]. The mean age of the study population [58.7% (n = 553) males] was 46.9 years. The most common indication for BAL was suspected pulmonary infection. Right upper lobes and middle lobes were the commonest sampled lobes. The optimal yield was similar in all the groups [MST (35.6%) vs MS (42.2%) vs WMS (36.5%); P = 0.27]. A significantly higher proportion of patients had BALF return >30% (P = 0.005) in the WMS (54.2%) and MS (54%) than in the MST arm (42.9%). The absolute and the percentage volume of BALF was also higher in WMS and MS than in the MST arm. There was no difference in the complication rate or other secondary outcomes across the groups. Conclusion: We found no difference in the optimal yield of BAL or complications using any one of the 3 methods for BAL fluid retrieval.

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Bronchoalveolar Lavage

Cited by 3 publications

References 185 publications

Pathological Characteristics of Fiberoptic Bronchoscopy Procedure in Ulin General Hospital, Banjarmasin

Pathological Characteristics of Fiberoptic Bronchoscopy Procedure in Ulin General Hospital, Banjarmasin

Preparation and Findings in Diagnostic and Therapeutic Flexible Fiberoptic Bronchoscopy Procedures in Patients with COVID-19

A Randomized Control Trial Comparing the Yield of Bronchoalveolar Lavage Using Three Different Techniques in Patients Undergoing Flexible Bronchoscopy (BAL-3T)

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