Bronchoscopy and Bronchoalveolar Lavage in Children with Lower Airway Infection and Most Common Pathologic Microorganisms Isolated

Selimović, Amina; Pejčić, Tatjana; Rančić, Milan; Mujičić, Ermina; Bajroviç, Kasım

doi:10.2478/v10283-012-0003-9

Cited by 1 publication

(2 citation statements)

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“…The three major diseases are dermatomyositis, polymyositis and inclusion body myositis. Dermatomyositis is a systematic autoimmune connective tissue disease, which most frequently affects the skin and muscles, but may also affect the joints, esophagus, lungs, and heart (1,2). The course of disease is difficult to predict, usually, it has a long course with remission and exacerbations (3).…”

Section: R E S U L T Smentioning

confidence: 99%

“…In most of the patients without lung disease, respiratory muscle weakness was accompanied by significant decreases in vital capacity, total lung capacity, and maximum voluntary ventilation, by significant increases in the residual volume and arterial carbon dioxide tension (PaCO2) and a greater likelihood of dependence on ventilations, atelectasis and pneumonia. Hypercapnia was particularly likely whenever respiratory muscle strength was less than 30% of its normal value, in uncomplicated myopathy and when vital capacity was less than 55% of the predicted volume in any patient (2,3). Pathogenesis: this is most likely a cellular automechanism, given that lymphocytes from the infected focal points of patients in vitro destroy the striated muscles.…”

Section: Introductionmentioning

confidence: 97%

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Re-expansion of an Atelectatic Lung through Flexible Bronchoscopy in a Child with Dermatomyositis and Celiac Disease

Selimović¹,

Rančić²,

Mujičić³

et al. 2013

Acta Facultatis Medicae Naissensis

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This paper describes the utility of flexible bronchoscopy in a sick child diagnosed with dermatomyositis, celiac disease. Mucus plug is a common medical cause of lung atelectasis. Due to deteriorated respiratory condition, the child was highly febrile, cyanotic, liver 6-7 cm, palpable under the right rib arch. We described a child with dermatomyositis and lung atelectasis. Atelectasis causes difficulty breathing and decreased oxygen saturation, so the child was intubated and put on a complete mechanical ventilation.Before intubation, the number of respirations exceeded 40/min, O2 saturation on the pulse oximeter fell under 73%. Pulse rate was 173/min, blood pressure 94/37 mmHg. Before intubation, the gas analysis of blood showed: Ph below 7.30 and pCO2 9 kPa, pO2 in the blood below 4.9 kPa. After flexible bronchoscopy was performed, therapeutic and diagnostic, lung re-expansion was enabled. After performed bronchoalveolar lavage with 0.9% NaCL 1 ml per kg TT, twice repeated, corticosteroids were introduced at the site of the changed mucus membrane. Mechanical ventilation parameters: Fio2, number of respirations and inspiratory pressure decreased. Values of gas analysis: ph improvement above 7.30 Pco2 3.6kPa, pO2 in the blood 11. O2 saturation 95%, pulse rate 120/min. The five-year-old child patient was extubated five days after bronchoscopy and was transferred to the standard Pulmonology Ward. Blood derivatives were obtained on several occasions. The condition improved, methotrexat therapy was introduced, with corticosteroids once a week, 3x40 mg i.v., on other week days Pronison 5 mg 4x1.

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Section: R E S U L T Smentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%