Brown garlic: A nutritionally improved garlic with therapeutic value in asthma treatment via modulation of S-nitrosothiols

Lee, Geun-Mo; Mun, Bong-Gyu; Hussain, Adil; Kim, Eungyung; Lee, Da-Sol; Kim, Myoung Ok; Yun, Byung-Wook

doi:10.1016/j.heliyon.2024.e36976

Heliyon

2024

DOI: 10.1016/j.heliyon.2024.e36976

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Brown garlic: A nutritionally improved garlic with therapeutic value in asthma treatment via modulation of S-nitrosothiols

Geun-Mo Lee,

Bong-Gyu Mun,

Adil Hussain

et al.

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Polysaccharides from fermented garlic attenuate high‐fat diet‐induced obesity in mice through gut microbes

Liu,

Li,

et al. 2024

Journal of Food Science

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The weight loss and lipid‐lowering effects of fermented garlic polysaccharides (BGP) in obese mice were analyzed by detecting the intestinal flora and short‐chain fatty acids. An obesity model was established by feeding mice a high‐fat diet (HFD) for 8 weeks. After euthanasia, biochemical index testing and hematoxylin and eosin staining were performed. Spearman analysis was used to assess the relationship between the 16S rRNA sequencing results and the fatty acid content in mouse feces. Compared with the obese model mice, the BGP group had significantly reduced body weight and serum triglycerides, total cholesterol, low‐density lipoprotein cholesterol, malondialdehyde, and free fatty acids in the serum. Moreover, BGP reversed HFD‐induced gut microbiota dysbiosis, as indicated by the elevated populations of Paraclostridium, Lachnospiraceae_UCG_006, Enterorhabdus, and Lachnospiraceae‐NK4A136. BGP also significantly increased the contents of acetic, propionic, butyric, and valeric acids. These results indicate that BGP may serve as a potential prebiotic agent that modulates particular bacteria in the gut and their byproducts that play a crucial role in preventing diseases associated with obesity.

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Polysaccharides from fermented garlic attenuate high‐fat diet‐induced obesity in mice through gut microbes

Liu,

Li,

et al. 2024

Journal of Food Science

View full text Add to dashboard Cite

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Brown garlic: A nutritionally improved garlic with therapeutic value in asthma treatment via modulation of S-nitrosothiols

Cited by 1 publication

References 34 publications

Polysaccharides from fermented garlic attenuate high‐fat diet‐induced obesity in mice through gut microbes

Polysaccharides from fermented garlic attenuate high‐fat diet‐induced obesity in mice through gut microbes

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