Brown-Mclean syndrome in an aphakic patient with homocystinuria

Abstract

Brown-McLean syndrome not reported in association with homocystinuria and generally occurs in patients with long-term aphakia. Presented as peripheral corneal edema with central clear cornea tends to spare vision without the need of any surgical intervention. The purpose of reporting such a rare condition as a first case of Brown-McLean syndrome associated with systemic disease of homocystinuria. Brown-McLean Syndrome in a patient with homocystinuria generally occurs in patients with long-term aphakia after different modalities of surgical intervention. A high clinical suspicion and regular follow-up is warranted for patients with systemic diseases who are aphakic or present with a subluxated lens for early intervention and better prognosis if needed.

Brown McLean syndrome after congenital glaucoma surgery, unique case report and a literature review

“… 8 In 2021, Alenaze and colleagues reported a case of BMS in an aphakic patient with homocystinuria. 9 Two cases were reported by Lee and colleagues in 2021 where patients had undergone cataract extraction. The first was a Marfan syndrome case who was left aphakic and developed BMS four years later, with characteristics confirmed by specular microscopy.…”