Brown Recluse Spider Bites of the Upper Extremity

Epidemiological and clinical manifestations of patients hospitalized with brown recluse spider bite

“…In one previous study, no relationship between initial lesion size and long‐term outcome was observed 19 . The local reaction of the brown recluse spider bite described in our study varied considerably from moderate to severe skin necrosis with ulceration.…”

Development of dapsone toxicity in patients with inflammatory dermatoses: Activity of acetylation and hydroxylation of dapsone as risk factors

“…Dapsone (DDS, diamino‐diphenylsulfone) is used in the treatment of leprosy and chloroquine‐resistant malaria, as well as for the management of pneumocystitis carinii in patients with acquired immunodeficiency syndrome (AIDS). In addition, it is useful in the treatment of inflammatory dermatoses such as dermatitis herpetiformis, bullous pemphigoid, and ulcers caused by brown recluse spider bites 1 , 2 , 3 , 4 , 5 , 6 , 7 . However, adverse drug reactions, particularly methemoglobinemia, hemolysis, and neurologic effects (such as headache and nervousness) limit its usefulness 8 , 9 , 10 , 11 , 12 .…”

Uso de terapia VAC® para tratamiento de heridas por mordedura de araña reclusa café

“…Estos autores justifican este proceder en base a la observación de que la resección temprana del tejido necrótico puede incrementar y perpetuar la respuesta inflamatoria y por lo tanto, favorecer la extensión del área de pérdida de tejido (1,4). Sin embargo, hay otros autores que presentan muy buenos resultados tras realizar resección temprana de la lesión, con la idea de que se acelera la posterior reconstrucción y se disminuye el dolor, el tiempo de hospitalización del paciente y las secuelas posteriores (5).…”